Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts
Antifungal studies of Cymbopogon nardus were carried out against several different fungi and yeast. Cold extraction method employing organic solvents was used in this study. The filtered aqueous methanolic extract of the leaves was sequentially extracted with n-hexane, chloroform and ethanol resp...
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| Format: | Thesis |
| Language: | English |
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2004
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| Online Access: | http://eprints.usm.my/45251/ http://eprints.usm.my/45251/1/LI...Nik%20Aida%20Diana%20Binti%20Nik%20Zainuddin...2004...-24%20pages.pdf |
| _version_ | 1848880277186674688 |
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| author | Zainuddin, Nik Aida Diana Nik |
| author_facet | Zainuddin, Nik Aida Diana Nik |
| author_sort | Zainuddin, Nik Aida Diana Nik |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Antifungal studies of Cymbopogon nardus were carried out against several different
fungi and yeast. Cold extraction method employing organic solvents was used in this
study. The filtered aqueous methanolic extract of the leaves was sequentially
extracted with n-hexane, chloroform and ethanol respectively. Candida albicans,
Candida g/abrata, Candida tropicalis and Cryptococcus neoformans were selected as
test organisms. The chloroform extracts of Cymbopogon nardus was active against
Candida albicans, Candida glabrata and Candida tropicalis giving a clear zone of 0. 7-
0.8 em at different concentrations (0.01 mg/ml, 0.1 mg/ml and 1.0 mg/ml). The nhexane,
ethanol and methanol extract did not show any inhibitory activity against the
microorganisms tested except for Candida glabrata, where a clearing zone of 0.6-0.9
em was noted for the ethanol and methanol extracts at different concentrations. nHexane,
chloroform, ethanol and methanol extracts were active against
Cryptococcus neoformans at all the concentration tested. However, the growth
inhibitory effect of all the extracts are insignificant compared to the antibiotic
Amphotericin B. |
| first_indexed | 2025-11-15T18:00:34Z |
| format | Thesis |
| id | usm-45251 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:00:34Z |
| publishDate | 2004 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-452512019-08-20T08:20:33Z http://eprints.usm.my/45251/ Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts Zainuddin, Nik Aida Diana Nik RM Therapeutics. Pharmacology Antifungal studies of Cymbopogon nardus were carried out against several different fungi and yeast. Cold extraction method employing organic solvents was used in this study. The filtered aqueous methanolic extract of the leaves was sequentially extracted with n-hexane, chloroform and ethanol respectively. Candida albicans, Candida g/abrata, Candida tropicalis and Cryptococcus neoformans were selected as test organisms. The chloroform extracts of Cymbopogon nardus was active against Candida albicans, Candida glabrata and Candida tropicalis giving a clear zone of 0. 7- 0.8 em at different concentrations (0.01 mg/ml, 0.1 mg/ml and 1.0 mg/ml). The nhexane, ethanol and methanol extract did not show any inhibitory activity against the microorganisms tested except for Candida glabrata, where a clearing zone of 0.6-0.9 em was noted for the ethanol and methanol extracts at different concentrations. nHexane, chloroform, ethanol and methanol extracts were active against Cryptococcus neoformans at all the concentration tested. However, the growth inhibitory effect of all the extracts are insignificant compared to the antibiotic Amphotericin B. 2004 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45251/1/LI...Nik%20Aida%20Diana%20Binti%20Nik%20Zainuddin...2004...-24%20pages.pdf Zainuddin, Nik Aida Diana Nik (2004) Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RM Therapeutics. Pharmacology Zainuddin, Nik Aida Diana Nik Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts |
| title | Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts |
| title_full | Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts |
| title_fullStr | Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts |
| title_full_unstemmed | Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts |
| title_short | Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts |
| title_sort | studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts |
| topic | RM Therapeutics. Pharmacology |
| url | http://eprints.usm.my/45251/ http://eprints.usm.my/45251/1/LI...Nik%20Aida%20Diana%20Binti%20Nik%20Zainuddin...2004...-24%20pages.pdf |