Development Of A Nomogram To Guide The Monitoring Of Once Daily Dosing Gentamicin Regimen In Hospital Melaka
The exact starting dose used in once daily dosing gentamicin (ODD) has not been clearly defined but it is typically equivalent to the sum of doses traditionally used with conventional dosing over a 24-hour period. However, most literatures have recommended a dosing range of 5 to 7 mg/kg/day. D...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2013
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| Online Access: | http://eprints.usm.my/45185/ http://eprints.usm.my/45185/1/Nursahjohana%20Binti%20Md%20Sahak24.pdf |
| _version_ | 1848880257929576448 |
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| author | Sahak, Nursahjohana Md |
| author_facet | Sahak, Nursahjohana Md |
| author_sort | Sahak, Nursahjohana Md |
| building | USM Institutional Repository |
| collection | Online Access |
| description | The exact starting dose used in once daily dosing gentamicin (ODD) has not been
clearly defined but it is typically equivalent to the sum of doses traditionally used with
conventional dosing over a 24-hour period. However, most literatures have
recommended a dosing range of 5 to 7 mg/kg/day. Despite these recommendations,
anecdotal reports have shown that the usual dose used in ODD in Malaysia was much
lower, with an average of 3.5 mg/kg. Therefore, clinical and bacteriological cures
maybe different. Consequently, published monitoring method of ODD gentamicin in the
literature may not be applicable in local setting.
This study was carried out to evaluate the practice of ODD gentamicin, to
determine its pharmacokinetic parameters and to develop a simple monitoring method
applicable in Hospital Melaka. |
| first_indexed | 2025-11-15T18:00:15Z |
| format | Thesis |
| id | usm-45185 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:00:15Z |
| publishDate | 2013 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-451852019-08-05T03:20:33Z http://eprints.usm.my/45185/ Development Of A Nomogram To Guide The Monitoring Of Once Daily Dosing Gentamicin Regimen In Hospital Melaka Sahak, Nursahjohana Md RS1-441 Pharmacy and materia medica The exact starting dose used in once daily dosing gentamicin (ODD) has not been clearly defined but it is typically equivalent to the sum of doses traditionally used with conventional dosing over a 24-hour period. However, most literatures have recommended a dosing range of 5 to 7 mg/kg/day. Despite these recommendations, anecdotal reports have shown that the usual dose used in ODD in Malaysia was much lower, with an average of 3.5 mg/kg. Therefore, clinical and bacteriological cures maybe different. Consequently, published monitoring method of ODD gentamicin in the literature may not be applicable in local setting. This study was carried out to evaluate the practice of ODD gentamicin, to determine its pharmacokinetic parameters and to develop a simple monitoring method applicable in Hospital Melaka. 2013-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45185/1/Nursahjohana%20Binti%20Md%20Sahak24.pdf Sahak, Nursahjohana Md (2013) Development Of A Nomogram To Guide The Monitoring Of Once Daily Dosing Gentamicin Regimen In Hospital Melaka. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Sahak, Nursahjohana Md Development Of A Nomogram To Guide The Monitoring Of Once Daily Dosing Gentamicin Regimen In Hospital Melaka |
| title | Development Of A Nomogram To Guide
The Monitoring Of Once Daily Dosing
Gentamicin Regimen
In Hospital Melaka |
| title_full | Development Of A Nomogram To Guide
The Monitoring Of Once Daily Dosing
Gentamicin Regimen
In Hospital Melaka |
| title_fullStr | Development Of A Nomogram To Guide
The Monitoring Of Once Daily Dosing
Gentamicin Regimen
In Hospital Melaka |
| title_full_unstemmed | Development Of A Nomogram To Guide
The Monitoring Of Once Daily Dosing
Gentamicin Regimen
In Hospital Melaka |
| title_short | Development Of A Nomogram To Guide
The Monitoring Of Once Daily Dosing
Gentamicin Regimen
In Hospital Melaka |
| title_sort | development of a nomogram to guide
the monitoring of once daily dosing
gentamicin regimen
in hospital melaka |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/45185/ http://eprints.usm.my/45185/1/Nursahjohana%20Binti%20Md%20Sahak24.pdf |