Methanolic extract of Abrus precatorius promotes breast cancer MDA-MB-231 cell death by inducing cell cycle arrest at G0/G1 and upregulating Bax

QR Code

Methanolic extract of Abrus precatorius promotes breast cancer MDA-MB-231 cell death by inducing cell cycle arrest at G0/G1 and upregulating Bax

Objective: To determine the anti-proliferative activity of Abrus precatorius (A. precatorius) leaf extracts and their effect on cell death. Methods: A. precatorius leaves were extracted successively with hexane, ethyl acetate and methanol by Soxhlet extraction. Aqueous extract was prepared by dec...

Full description

Bibliographic Details
Main Authors:	Ismail, Norzila, Ibrahim, Wan Suriyani Wan, Salleh, Siti Farhanah Mohd, Yajid, Aidy Irman, Wong, Michael Pak-Kai, Hashim, Mohd Nizam Md
Format:	Article
Language:	English
Published:	Elsevier 2019
Subjects:	RC254-282 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://eprints.usm.my/44687/ http://eprints.usm.my/44687/1/AsianPacJTropBiomed_2019_9_6_249_260397-OCR%20-2.pdf

Similar Items

Methanolic extract of Abrus precatorius promotes breast cancer MDA-MB-231 cell death by inducing cell cycle arrest at G0/G1 and upregulating Bax
by: Ibrahim, Wan Suriyani Wan
Published: (2019)

GC-MS Analysis of Phytochemical Compounds in Aqueous Leaf Extract of Abrus Precatorius
by: Ibrahim, Wan Suriyani Wan, et al.
Published: (2018)

Phytochemical characterization, induction of apoptosis and activation of natural killer (nk) cells by abrus precatorius leaves extract on human breast cancer cell line
by: Ibrahim, Wan Suriyani Faliq Adeeba Wan
Published: (2020)

Anti-proliferation of MDA-MB-231 cells by Averrhoa bilimbi extract is associated with G0/G1 perturbation and mitochondria-mediated apoptosis independent of p53
by: Yan, See Wan, et al.
Published: (2017)

Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231
by: Abd Rahman, Napsiah, et al.
Published: (2016)

Citral induced apoptosis in MDA-MB-231 spheroid cells
by: Rosli, Rozita, et al.
Published: (2018)

Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis
by: Armania, Nurdin, et al.
Published: (2013)

Pereskia bleo leaves extract induces cell death via cell cycle arrest and apoptosis in cervical cancer cells hela
by: Salleh, Siti Farhanah Mohd, et al.
Published: (2019)

Effects of chemically synthesized kava-kava (Piper methysticum g.forst) flavokawain A and B on the apoptotic and metastatic process of MCF -7 and MDA - MB231 cells in vitro and 4T1 cells in vivo
by: Abu, Nadiah
Published: (2014)

The effects of valproic acid on navi.5 gene expression in mda-mb- 231 cells
by: Kandivan, Hemalatha
Published: (2016)

Cell cycle arrest and apoptosis- inducing effect of Dicranopteris linearis (Burm.F.) Underw. leaf crude extract in MDA-MB-231 cell
by: Baharuddin, Aifaa Akmal
Published: (2018)

Xanthorrhizol Induces Apoptosis Via the Up-regulation of Bax and p53 in HeLa Cells
by: Ismail, Norzila, et al.
Published: (2005)

Xanthorrhizol Induces Apoptosis Via the Up-regulation of Bax and p53 in HeLa Cells
by: Ismail, Norzila, et al.
Published: (2005)

Cytotoxic effects of 7-geranyloxycinnamic acid isolated from Melicope lunu-ankenda (Gaertn) T.G.Hartley leaves on breast cancer cell lines (MCF-7 and MDA-MB-231
by: Eliaser, Enas Mohamed Abdaallah
Published: (2022)

Effect of linoleic acid of Nigella sativa on MDA-MB-231 human breast cancer cells.
by: G. K., Hasanzadeh, et al.
Published: (2011)

Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
by: Nadiah, Abu, et al.
Published: (2016)

Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases in vitro
by: Abu, Nadiah, et al.
Published: (2016)

Ampelopsin E reduces the invasiveness of the triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu, et al.
Published: (2019)

The effects of 2-methoxy-1,4-naphthoquinone (mnq) on glucose metabolism of mda-mb-231 cells
by: Daud, Syukriyah Mat
Published: (2020)

Effects of knocking-down HIF-la on migration in human breast cancer cell MDA-MB-231
by: Rashid, Nur Sabrina Abd
Published: (2015)

Exosomal-microRNA transcriptome profiling of parental and CSC-like MDA-MB-231 cells in response to cisplatin treatment
by: Koh, May Zie, et al.
Published: (2022)

Dicranopteris linearis extract inhibits the proliferation of human breast cancer cell line (MDA-MB-231) via induction of S-phase arrest and apoptosis
by: Baharuddin, Aifaa Akmal, et al.
Published: (2018)

Design, synthesis of flavokawain b derivative and their cytotoxic effects on MCF-7 and MDA-MB-231 cell lines
by: Addila, Abu Bakar
Published: (2018)

Oncolytic Effect Of Newcastle Disease Virus On The Mcf-7 And Mda-Mb-231 Breast Cancer Cell Lines
by: Meyyappan, Narayani
Published: (2003)

Curcumin from turmeric (Curcuma longa) induced apoptosis in human mammary carcinoma cells (MDA-MB-231)
by: Saiful Yazan, Latifah, et al.
Published: (2006)

Effects of ampelopsin E towards the invasiveness of triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu
Published: (2019)

The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells
by: Etti, Imaobong Christopher, et al.
Published: (2017)

Treatment of MCF-7 and MDA-MB-231 human breast cancer cell lines with erythropoietin, doxorubicin and their combination
by: Radwan, Esam M.
Published: (2015)

Establishment of hypoxia-induced invadopodia model and phenotype characterisation of MDA-MB- 231 breast cancer cell line
by: Hamad, Hamad Hamad Ali
Published: (2019)

Therapeutic potential of albumin nanoparticles encapsulated visnagin in MDA-MB-468 triple-negative breast cancer cells
by: Alsrhani, Abdullah, et al.
Published: (2023)

High-dose edible bird’s nest extract (EBN) upregulates LDL-R via suppression of HMGCR gene expression in HepG2 cell lines
by: Mohd Noor Akmal,, et al.
Published: (2020)

Effect of ximenynic acid on cell cycle arrest and apoptosis and COX-1 in HepG2 cells
by: Cai, F., et al.
Published: (2016)

Assessment of cytotoxicity potency of paclitaxel in combination with Clinacanthus Nutans extracts on human MDA-MB-231 breast cancer cells
by: Nur Hasnieza Mohd Rosli,, et al.
Published: (2018)

Extracts of Hypsizygus tessellatus (white var.) caps inhibited MCF-7 and MDA-MB-231 cell lines proliferation
by: Ukaegbu, Chinonso Ishmael, et al.
Published: (2018)

Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-mb231 breast cancer cells
by: Radwan, Esam M., et al.
Published: (2016)

mRNA expression of Somatostatin receptors 1-5 in MCF7 and MDA-MB231 breast cancer cells
by: Mahmoud, Alkhansa, et al.
Published: (2021)

Effects of co-loaded doxorubicin and thymoquinone calcium carbonate nanoparticles on MDA MB231 breast cancer stem cells
by: Muibat, Ibiyeye Kehinde
Published: (2019)

Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231
by: Siah, Poh Chiew
Published: (2017)

Anti cancer activity of plant extracts on MDA-MB231
by: Yussoff, Seri Wahyuni
Published: (2015)

Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines
by: Addila, Abu Bakar, et al.
Published: (2018)