Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation

We examined association between the changes in blood oxidative stress level/activity and the changes in memory performance in postmenopausal women receiving Tualang honey (TH). The verbal learning and memory performances of thirty nine postmenopausal women were assessed using the Malay version of...

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Main Authors: Shafin, Nazlahshaniza, Zakaria, Rahimah, Othman, Zahiruddin, Hussain, Nik Hazlina Nik
Format: Article
Language:English
Published: Research Publisher Inc. 2014
Subjects:
Online Access:http://eprints.usm.my/44652/
http://eprints.usm.my/44652/1/2014-_JBPR_improved_blood_oxidative-libre.pdf
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author Shafin, Nazlahshaniza
Zakaria, Rahimah
Othman, Zahiruddin
Hussain, Nik Hazlina Nik
author_facet Shafin, Nazlahshaniza
Zakaria, Rahimah
Othman, Zahiruddin
Hussain, Nik Hazlina Nik
author_sort Shafin, Nazlahshaniza
building USM Institutional Repository
collection Online Access
description We examined association between the changes in blood oxidative stress level/activity and the changes in memory performance in postmenopausal women receiving Tualang honey (TH). The verbal learning and memory performances of thirty nine postmenopausal women were assessed using the Malay version of the Auditory Verbal Learning Test (MVAVLT) and their oxidative stress levels/activities were determined using commercially available kits before and 16 weeks after TH supplementation. The plasma glutathione peroxidase (GPx) and catalase (CAT) activities were considerably increased but the 4-hydroxynonenal (4-HNE) level was notably decreased after 16 weeks of TH supplementation. There were positive correlations between the changes in plasma GPx and the changes in trial A6 scores (r = 0.48, P < 0.05) and between the changes in plasma CAT and the changes in recognition score (r = 0.32, P < 0.05). TH supplementation for 16 weeks reduced blood oxidative stress but most of the changes in blood oxidative stress level/activity were not significantly correlated with the changes in memory performance.
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spelling usm-446522019-06-18T04:00:54Z http://eprints.usm.my/44652/ Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation Shafin, Nazlahshaniza Zakaria, Rahimah Othman, Zahiruddin Hussain, Nik Hazlina Nik RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry We examined association between the changes in blood oxidative stress level/activity and the changes in memory performance in postmenopausal women receiving Tualang honey (TH). The verbal learning and memory performances of thirty nine postmenopausal women were assessed using the Malay version of the Auditory Verbal Learning Test (MVAVLT) and their oxidative stress levels/activities were determined using commercially available kits before and 16 weeks after TH supplementation. The plasma glutathione peroxidase (GPx) and catalase (CAT) activities were considerably increased but the 4-hydroxynonenal (4-HNE) level was notably decreased after 16 weeks of TH supplementation. There were positive correlations between the changes in plasma GPx and the changes in trial A6 scores (r = 0.48, P < 0.05) and between the changes in plasma CAT and the changes in recognition score (r = 0.32, P < 0.05). TH supplementation for 16 weeks reduced blood oxidative stress but most of the changes in blood oxidative stress level/activity were not significantly correlated with the changes in memory performance. Research Publisher Inc. 2014-06 Article PeerReviewed application/pdf en http://eprints.usm.my/44652/1/2014-_JBPR_improved_blood_oxidative-libre.pdf Shafin, Nazlahshaniza and Zakaria, Rahimah and Othman, Zahiruddin and Hussain, Nik Hazlina Nik (2014) Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation. Journal of Biochemical and Pharmacological Research, 2 (2). pp. 110-116. ISSN 2168-8761 http://researchpub.org/journal/jbpr/archives_vol2_no2.html
spellingShingle RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Shafin, Nazlahshaniza
Zakaria, Rahimah
Othman, Zahiruddin
Hussain, Nik Hazlina Nik
Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation
title Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation
title_full Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation
title_fullStr Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation
title_full_unstemmed Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation
title_short Improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving Tualang honey supplementation
title_sort improved blood oxidative status is not associated with better memory performance in postmenopausal women receiving tualang honey supplementation
topic RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
url http://eprints.usm.my/44652/
http://eprints.usm.my/44652/
http://eprints.usm.my/44652/1/2014-_JBPR_improved_blood_oxidative-libre.pdf