Tualang Honey Supplementation Reduces Blood Oxidative Stress Levels/Activities in Postmenopausal Women
his study aimed to investigate the ability of Tualang honey (TH), a phytoestrogen, to reduce blood oxidative stress levels/activities in postmenopausal women and compared the efects with the standard estrogen progestin therapy (EPT). A total of 78 healthy postmenopausal women were randomly assigne...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Publishing Corporation
2014
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| Online Access: | http://eprints.usm.my/44530/ http://eprints.usm.my/44530/1/2014_ISRN_Oxidative_Medicine_-_TH_suppl-libre.pdf |
| _version_ | 1848880085344452608 |
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| author | Shafin, Nazlahshaniza Othman, Zahiruddin Zakaria, Rahimah Hussain, Nik Hazlina Nik |
| author_facet | Shafin, Nazlahshaniza Othman, Zahiruddin Zakaria, Rahimah Hussain, Nik Hazlina Nik |
| author_sort | Shafin, Nazlahshaniza |
| building | USM Institutional Repository |
| collection | Online Access |
| description | his study aimed to investigate the ability of Tualang honey (TH), a phytoestrogen, to reduce blood oxidative stress levels/activities
in postmenopausal women and compared the efects with the standard estrogen progestin therapy (EPT). A total of 78 healthy
postmenopausal women were randomly assigned to one of two groups; EPT group received Femoston conti 1/5 (1mg 17�-
estradiol and 5mg dydrogesterone), and TH group, received 20 g of TH supplement daily for 16 weeks. he reduced glutathione to
oxidized glutathione ratio (GSH:GSSG), plasma glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD), and
�-hydroxynonenal (�-HNE) levels/activities were measured at pre- and postinterventions using commercially available kits. he
plasma GPx and CAT activities were notably increased, and plasma �-HNE level was signiicantly decreased in postmenopausal
women who received EPT and TH supplementation. TH supplementation for 16 weeks was able to reduce blood oxidative stress
levels/activities of postmenopausal women comparable to those who received EPT. hus, TH has a potential to be used as
antioxidant therapy to combat oxidative stress-induced neurodegenerative diseases.his trial is registered with NCT01300676. |
| first_indexed | 2025-11-15T17:57:31Z |
| format | Article |
| id | usm-44530 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T17:57:31Z |
| publishDate | 2014 |
| publisher | Hindawi Publishing Corporation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-445302019-06-04T04:11:09Z http://eprints.usm.my/44530/ Tualang Honey Supplementation Reduces Blood Oxidative Stress Levels/Activities in Postmenopausal Women Shafin, Nazlahshaniza Othman, Zahiruddin Zakaria, Rahimah Hussain, Nik Hazlina Nik RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry his study aimed to investigate the ability of Tualang honey (TH), a phytoestrogen, to reduce blood oxidative stress levels/activities in postmenopausal women and compared the efects with the standard estrogen progestin therapy (EPT). A total of 78 healthy postmenopausal women were randomly assigned to one of two groups; EPT group received Femoston conti 1/5 (1mg 17�- estradiol and 5mg dydrogesterone), and TH group, received 20 g of TH supplement daily for 16 weeks. he reduced glutathione to oxidized glutathione ratio (GSH:GSSG), plasma glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD), and �-hydroxynonenal (�-HNE) levels/activities were measured at pre- and postinterventions using commercially available kits. he plasma GPx and CAT activities were notably increased, and plasma �-HNE level was signiicantly decreased in postmenopausal women who received EPT and TH supplementation. TH supplementation for 16 weeks was able to reduce blood oxidative stress levels/activities of postmenopausal women comparable to those who received EPT. hus, TH has a potential to be used as antioxidant therapy to combat oxidative stress-induced neurodegenerative diseases.his trial is registered with NCT01300676. Hindawi Publishing Corporation 2014 Article PeerReviewed application/pdf en http://eprints.usm.my/44530/1/2014_ISRN_Oxidative_Medicine_-_TH_suppl-libre.pdf Shafin, Nazlahshaniza and Othman, Zahiruddin and Zakaria, Rahimah and Hussain, Nik Hazlina Nik (2014) Tualang Honey Supplementation Reduces Blood Oxidative Stress Levels/Activities in Postmenopausal Women. ISRN Oxidative Medicine, 2014 (364836). pp. 1-4. ISSN 2314-6400 http://dx.doi.org/10.1155/2014/364836 |
| spellingShingle | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry Shafin, Nazlahshaniza Othman, Zahiruddin Zakaria, Rahimah Hussain, Nik Hazlina Nik Tualang Honey Supplementation Reduces Blood Oxidative Stress Levels/Activities in Postmenopausal Women |
| title | Tualang Honey Supplementation Reduces Blood Oxidative
Stress Levels/Activities in Postmenopausal Women |
| title_full | Tualang Honey Supplementation Reduces Blood Oxidative
Stress Levels/Activities in Postmenopausal Women |
| title_fullStr | Tualang Honey Supplementation Reduces Blood Oxidative
Stress Levels/Activities in Postmenopausal Women |
| title_full_unstemmed | Tualang Honey Supplementation Reduces Blood Oxidative
Stress Levels/Activities in Postmenopausal Women |
| title_short | Tualang Honey Supplementation Reduces Blood Oxidative
Stress Levels/Activities in Postmenopausal Women |
| title_sort | tualang honey supplementation reduces blood oxidative
stress levels/activities in postmenopausal women |
| topic | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| url | http://eprints.usm.my/44530/ http://eprints.usm.my/44530/ http://eprints.usm.my/44530/1/2014_ISRN_Oxidative_Medicine_-_TH_suppl-libre.pdf |