Potential Role of Honey in Learning and Memory

The composition and physicochemical properties of honey are variable depending on its floral source and often named according to the geographical location. The potential medicinal benefits of Tualang honey, a multifloral jungle honey found in Malaysia, have recently been attracting attention because...

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Main Authors: Othman, Zahiruddin, Zakaria, Rahimah, Hussain, Nik Hazlina Nik, Hassan, Asma', Shafin, Nazlahshaniza, Al-Rahbi, Badriya, Ahmad, Asma Hayati
Format: Article
Language:English
Published: MDPI 2015
Subjects:
Online Access:http://eprints.usm.my/44322/
http://eprints.usm.my/44322/1/MedSci%202015%3B3%282%293-15%20Potential%20Role%20of%20TH.pdf
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author Othman, Zahiruddin
Zakaria, Rahimah
Hussain, Nik Hazlina Nik
Hassan, Asma'
Shafin, Nazlahshaniza
Al-Rahbi, Badriya
Ahmad, Asma Hayati
author_facet Othman, Zahiruddin
Zakaria, Rahimah
Hussain, Nik Hazlina Nik
Hassan, Asma'
Shafin, Nazlahshaniza
Al-Rahbi, Badriya
Ahmad, Asma Hayati
author_sort Othman, Zahiruddin
building USM Institutional Repository
collection Online Access
description The composition and physicochemical properties of honey are variable depending on its floral source and often named according to the geographical location. The potential medicinal benefits of Tualang honey, a multifloral jungle honey found in Malaysia, have recently been attracting attention because of its reported beneficial effects in various diseases. This paper reviews the effects of honey, particularly Tualang honey, on learning and memory. Information regarding the effects of Tualang honey on learning and memory in human as well as animal models is gleaned to hypothesize its underlying mechanisms. These studies show that Tualang honey improves morphology of memory-related brain areas, reduces brain oxidative stress, increases brain-derived neurotrophic factor (BDNF) and acetylcholine (ACh) concentrations, and reduces acetylcholinesterase (AChE) in the brain homogenates. Its anti-inflammatory roles in reducing inflammatory trigger and microglial activation have yet to be investigated.
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spelling usm-443222019-05-13T08:16:31Z http://eprints.usm.my/44322/ Potential Role of Honey in Learning and Memory Othman, Zahiruddin Zakaria, Rahimah Hussain, Nik Hazlina Nik Hassan, Asma' Shafin, Nazlahshaniza Al-Rahbi, Badriya Ahmad, Asma Hayati RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry The composition and physicochemical properties of honey are variable depending on its floral source and often named according to the geographical location. The potential medicinal benefits of Tualang honey, a multifloral jungle honey found in Malaysia, have recently been attracting attention because of its reported beneficial effects in various diseases. This paper reviews the effects of honey, particularly Tualang honey, on learning and memory. Information regarding the effects of Tualang honey on learning and memory in human as well as animal models is gleaned to hypothesize its underlying mechanisms. These studies show that Tualang honey improves morphology of memory-related brain areas, reduces brain oxidative stress, increases brain-derived neurotrophic factor (BDNF) and acetylcholine (ACh) concentrations, and reduces acetylcholinesterase (AChE) in the brain homogenates. Its anti-inflammatory roles in reducing inflammatory trigger and microglial activation have yet to be investigated. MDPI 2015 Article PeerReviewed application/pdf en http://eprints.usm.my/44322/1/MedSci%202015%3B3%282%293-15%20Potential%20Role%20of%20TH.pdf Othman, Zahiruddin and Zakaria, Rahimah and Hussain, Nik Hazlina Nik and Hassan, Asma' and Shafin, Nazlahshaniza and Al-Rahbi, Badriya and Ahmad, Asma Hayati (2015) Potential Role of Honey in Learning and Memory. Medical Sciences, 3 (2). pp. 3-15. ISSN 2076-3271 https://www.mdpi.com/2076-3271/3/2/3
spellingShingle RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Othman, Zahiruddin
Zakaria, Rahimah
Hussain, Nik Hazlina Nik
Hassan, Asma'
Shafin, Nazlahshaniza
Al-Rahbi, Badriya
Ahmad, Asma Hayati
Potential Role of Honey in Learning and Memory
title Potential Role of Honey in Learning and Memory
title_full Potential Role of Honey in Learning and Memory
title_fullStr Potential Role of Honey in Learning and Memory
title_full_unstemmed Potential Role of Honey in Learning and Memory
title_short Potential Role of Honey in Learning and Memory
title_sort potential role of honey in learning and memory
topic RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
url http://eprints.usm.my/44322/
http://eprints.usm.my/44322/
http://eprints.usm.my/44322/1/MedSci%202015%3B3%282%293-15%20Potential%20Role%20of%20TH.pdf