Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel
The leaves of Mitragyna speciosa Korth (M. speciosa), commonly known as ketum in Malaysia, have been widely used to treat common illnesses such as intestinal infections, muscle pain, cough, diarrhea, diabetes, hypertension and to improve blood circulation. Nevertheless, there are growing concerns ab...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2018
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/44133/ http://eprints.usm.my/44133/1/TAY%20YEA%20LU.pdf |
| _version_ | 1848879983049572352 |
|---|---|
| author | Tay, Yea Lu |
| author_facet | Tay, Yea Lu |
| author_sort | Tay, Yea Lu |
| building | USM Institutional Repository |
| collection | Online Access |
| description | The leaves of Mitragyna speciosa Korth (M. speciosa), commonly known as ketum in Malaysia, have been widely used to treat common illnesses such as intestinal infections, muscle pain, cough, diarrhea, diabetes, hypertension and to improve blood circulation. Nevertheless, there are growing concerns about the safety and abuse or misuse potentials of the plant which exhibits addictive effects. The safety profile of the plant is not fully elucidated. The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit underlying cardiac rapidly delayed rectifier potassium current (IKr). |
| first_indexed | 2025-11-15T17:55:53Z |
| format | Thesis |
| id | usm-44133 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T17:55:53Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-441332019-04-18T06:52:47Z http://eprints.usm.my/44133/ Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel Tay, Yea Lu RS200-201 Pharmaceutical dosage forms The leaves of Mitragyna speciosa Korth (M. speciosa), commonly known as ketum in Malaysia, have been widely used to treat common illnesses such as intestinal infections, muscle pain, cough, diarrhea, diabetes, hypertension and to improve blood circulation. Nevertheless, there are growing concerns about the safety and abuse or misuse potentials of the plant which exhibits addictive effects. The safety profile of the plant is not fully elucidated. The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit underlying cardiac rapidly delayed rectifier potassium current (IKr). 2018-04 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/44133/1/TAY%20YEA%20LU.pdf Tay, Yea Lu (2018) Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | RS200-201 Pharmaceutical dosage forms Tay, Yea Lu Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title | Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_full | Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_fullStr | Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_full_unstemmed | Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_short | Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_sort | molecular mechanisms of mitragynine inhibition on herg1a/1b channel |
| topic | RS200-201 Pharmaceutical dosage forms |
| url | http://eprints.usm.my/44133/ http://eprints.usm.my/44133/1/TAY%20YEA%20LU.pdf |