Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay

Pathogenic bacteria such as Salmonella enterica serovar Typhi (S. Typhi) evade the host immune system and cause disease in their host by producing proteins known as virulence factors (VFs). When VFs are expressed in yeast Saccharomyces cerevisiae (S. cerevisiae), they have been observed to be detrim...

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Main Author: Koay, Ley Teng
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.usm.my/43660/
http://eprints.usm.my/43660/1/KOAY%20LEY%20TENG.pdf
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author Koay, Ley Teng
author_facet Koay, Ley Teng
author_sort Koay, Ley Teng
building USM Institutional Repository
collection Online Access
description Pathogenic bacteria such as Salmonella enterica serovar Typhi (S. Typhi) evade the host immune system and cause disease in their host by producing proteins known as virulence factors (VFs). When VFs are expressed in yeast Saccharomyces cerevisiae (S. cerevisiae), they have been observed to be detrimental to yeast cells (e.g. causing growth inhibition). In this sense, yeast can act as a sensitive indicator to identify VFs. There are still unidentified VFs and for those already reported, their roles in pathogenesis are still not completely understood.
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format Thesis
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institution Universiti Sains Malaysia
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language English
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publishDate 2018
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spelling usm-436602019-04-12T05:24:52Z http://eprints.usm.my/43660/ Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay Koay, Ley Teng R735-854 Medical education. Medical schools. Research Pathogenic bacteria such as Salmonella enterica serovar Typhi (S. Typhi) evade the host immune system and cause disease in their host by producing proteins known as virulence factors (VFs). When VFs are expressed in yeast Saccharomyces cerevisiae (S. cerevisiae), they have been observed to be detrimental to yeast cells (e.g. causing growth inhibition). In this sense, yeast can act as a sensitive indicator to identify VFs. There are still unidentified VFs and for those already reported, their roles in pathogenesis are still not completely understood. 2018-02 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43660/1/KOAY%20LEY%20TENG.pdf Koay, Ley Teng (2018) Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay. Masters thesis, Universiti Sains Malaysia.
spellingShingle R735-854 Medical education. Medical schools. Research
Koay, Ley Teng
Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay
title Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay
title_full Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay
title_fullStr Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay
title_full_unstemmed Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay
title_short Identification Of Salmonella enterica serovar Typhi Putative Virulence Factors Using A Yeast Growth Inhibition Assay
title_sort identification of salmonella enterica serovar typhi putative virulence factors using a yeast growth inhibition assay
topic R735-854 Medical education. Medical schools. Research
url http://eprints.usm.my/43660/
http://eprints.usm.my/43660/1/KOAY%20LEY%20TENG.pdf