Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae

Biotransformation of geraniol and nerol mediated by Saccharomyces cerevisiae was performed. Linalool and geraniol were mainly obtained from nerol using growing cells but only isomerisation to geraniol occurred using resting cells. Reductive biotransfomation of geraniol to citronellol was apparently...

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Main Author: Khor, Guat Kheng
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.usm.my/43357/
http://eprints.usm.my/43357/1/KHOR%20GUAT%20KHENG.pdf
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author Khor, Guat Kheng
author_facet Khor, Guat Kheng
author_sort Khor, Guat Kheng
building USM Institutional Repository
collection Online Access
description Biotransformation of geraniol and nerol mediated by Saccharomyces cerevisiae was performed. Linalool and geraniol were mainly obtained from nerol using growing cells but only isomerisation to geraniol occurred using resting cells. Reductive biotransfomation of geraniol to citronellol was apparently more effective with resting cells system. Combination of full factorial design with response surface methodology (RSM) was applied in order to evaluate the effects of cell density, substrate concentration and biotransformation time on product concentrations. The productivity increased proportionally with cell density. However, inhibition was observed at higher substrate concentrations.
first_indexed 2025-11-15T17:52:52Z
format Thesis
id usm-43357
institution Universiti Sains Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T17:52:52Z
publishDate 2011
recordtype eprints
repository_type Digital Repository
spelling usm-433572019-04-12T05:26:31Z http://eprints.usm.my/43357/ Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae Khor, Guat Kheng TP1-1185 Chemical technology Biotransformation of geraniol and nerol mediated by Saccharomyces cerevisiae was performed. Linalool and geraniol were mainly obtained from nerol using growing cells but only isomerisation to geraniol occurred using resting cells. Reductive biotransfomation of geraniol to citronellol was apparently more effective with resting cells system. Combination of full factorial design with response surface methodology (RSM) was applied in order to evaluate the effects of cell density, substrate concentration and biotransformation time on product concentrations. The productivity increased proportionally with cell density. However, inhibition was observed at higher substrate concentrations. 2011-08 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43357/1/KHOR%20GUAT%20KHENG.pdf Khor, Guat Kheng (2011) Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae. Masters thesis, Universiti Sains Malaysia.
spellingShingle TP1-1185 Chemical technology
Khor, Guat Kheng
Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_full Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_fullStr Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_full_unstemmed Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_short Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_sort biotransformation of cis/trans 3,7-dimethyl-2,6-octadien-1-ol mediated by saccharomyces cerevisiae
topic TP1-1185 Chemical technology
url http://eprints.usm.my/43357/
http://eprints.usm.my/43357/1/KHOR%20GUAT%20KHENG.pdf