Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds

In the present study, methanol seeds extract of Cassia fistula was assayed for antimicrobial and antioxidant activities, isolated and purified for bioactive compounds as well as evaluated for the toxicity effect. The seeds extract was tested for potential antimicrobial activity against medically imp...

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Main Author: Subramanion, Jo Thy Lachumy
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.usm.my/43351/
http://eprints.usm.my/43351/1/JO%20THY%20LACHUMY%20SUBRAMANION.pdf
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author Subramanion, Jo Thy Lachumy
author_facet Subramanion, Jo Thy Lachumy
author_sort Subramanion, Jo Thy Lachumy
building USM Institutional Repository
collection Online Access
description In the present study, methanol seeds extract of Cassia fistula was assayed for antimicrobial and antioxidant activities, isolated and purified for bioactive compounds as well as evaluated for the toxicity effect. The seeds extract was tested for potential antimicrobial activity against medically important Gram-positive and Gram-negative bacteria and fungal strains. The antimicrobial activity was determined by the disc diffusion and the broth dilution methods. The extract was effective on tested microorganism and the minimum inhibitory concentration (MIC) values were found in the range of 1.563-50.00 mg/mL. The seeds extract showed a favourable activity against pathogenic fungi C. albicans with MIC value 6.25 mg/mL, and this was confirmed by time kill assay study.
first_indexed 2025-11-15T17:52:51Z
format Thesis
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institution Universiti Sains Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T17:52:51Z
publishDate 2011
recordtype eprints
repository_type Digital Repository
spelling usm-433512019-04-12T05:26:30Z http://eprints.usm.my/43351/ Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds Subramanion, Jo Thy Lachumy LC5800-5808 Distance education. In the present study, methanol seeds extract of Cassia fistula was assayed for antimicrobial and antioxidant activities, isolated and purified for bioactive compounds as well as evaluated for the toxicity effect. The seeds extract was tested for potential antimicrobial activity against medically important Gram-positive and Gram-negative bacteria and fungal strains. The antimicrobial activity was determined by the disc diffusion and the broth dilution methods. The extract was effective on tested microorganism and the minimum inhibitory concentration (MIC) values were found in the range of 1.563-50.00 mg/mL. The seeds extract showed a favourable activity against pathogenic fungi C. albicans with MIC value 6.25 mg/mL, and this was confirmed by time kill assay study. 2011-10 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43351/1/JO%20THY%20LACHUMY%20SUBRAMANION.pdf Subramanion, Jo Thy Lachumy (2011) Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds. Masters thesis, Universiti Sains Malaysia.
spellingShingle LC5800-5808 Distance education.
Subramanion, Jo Thy Lachumy
Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds
title Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds
title_full Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds
title_fullStr Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds
title_full_unstemmed Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds
title_short Anticandidal, Antioxidant, Toxicity Studies And Isolation Of Compounds From Cassia Fistula Seeds
title_sort anticandidal, antioxidant, toxicity studies and isolation of compounds from cassia fistula seeds
topic LC5800-5808 Distance education.
url http://eprints.usm.my/43351/
http://eprints.usm.my/43351/1/JO%20THY%20LACHUMY%20SUBRAMANION.pdf