Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv
M. tuberculosis H37Ra, which was discovered in 1935, was derived from the virulent strain H37. In order to identify the factors that are correlated to virulence in M. tuberculosis H37Rv, 2D-gel profile of three virulent strains at culture grown for three time points (14, 28 and 50 days) were compare...
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| Format: | Thesis |
| Language: | English |
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2011
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| Online Access: | http://eprints.usm.my/43226/ http://eprints.usm.my/43226/1/ANG%20KAI%20CHEEN.pdf |
| _version_ | 1848879766366584832 |
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| author | Ang, Kai Cheen |
| author_facet | Ang, Kai Cheen |
| author_sort | Ang, Kai Cheen |
| building | USM Institutional Repository |
| collection | Online Access |
| description | M. tuberculosis H37Ra, which was discovered in 1935, was derived from the virulent strain H37. In order to identify the factors that are correlated to virulence in M. tuberculosis H37Rv, 2D-gel profile of three virulent strains at culture grown for three time points (14, 28 and 50 days) were compared with its avirulent counterpart M. tuberculosis H37Ra. A total of 250 protein spots were visualized by Coomassie blue staining. The protein profiles of the M. tuberculosis H37Rv and M. tuberculosis H37Ra were highly similar (R2~0.70), thirty one spots were found to be differentially expressed at 14, 28 and 50 days cultures, whereby 14 spots were identified from Tris extract and 17 spots were identified from TLB extract. |
| first_indexed | 2025-11-15T17:52:27Z |
| format | Thesis |
| id | usm-43226 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T17:52:27Z |
| publishDate | 2011 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-432262019-04-12T05:26:30Z http://eprints.usm.my/43226/ Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv Ang, Kai Cheen RS1-441 Pharmacy and materia medica M. tuberculosis H37Ra, which was discovered in 1935, was derived from the virulent strain H37. In order to identify the factors that are correlated to virulence in M. tuberculosis H37Rv, 2D-gel profile of three virulent strains at culture grown for three time points (14, 28 and 50 days) were compared with its avirulent counterpart M. tuberculosis H37Ra. A total of 250 protein spots were visualized by Coomassie blue staining. The protein profiles of the M. tuberculosis H37Rv and M. tuberculosis H37Ra were highly similar (R2~0.70), thirty one spots were found to be differentially expressed at 14, 28 and 50 days cultures, whereby 14 spots were identified from Tris extract and 17 spots were identified from TLB extract. 2011-09 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43226/1/ANG%20KAI%20CHEEN.pdf Ang, Kai Cheen (2011) Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Ang, Kai Cheen Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv |
| title | Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv |
| title_full | Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv |
| title_fullStr | Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv |
| title_full_unstemmed | Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv |
| title_short | Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv |
| title_sort | comparison of proteomes of avirulent mycobacterium tuberculosis h37ra and virulent mycobacterium tuberculosis h37rv |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/43226/ http://eprints.usm.my/43226/1/ANG%20KAI%20CHEEN.pdf |