The impact of CYP3A4 and CYP3A5 polymorphisms on anastrozole's pharmacokinetics and pharmacodynamics in post-menopausal breast cancer patients

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The impact of CYP3A4 and CYP3A5 polymorphisms on anastrozole's pharmacokinetics and pharmacodynamics in post-menopausal breast cancer patients

Breast cancer is the second most frequent cancer among all cancer types and is by far the commonest cancer in women. Anastrozole is one of the first line drugs of choice in the treatment of breast cancer and is believed to be superior to tamoxifen. However, a significant proportion of patients tr...

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Bibliographic Details
Main Author:	Abubakar, Murtala Bello
Format:	Thesis
Language:	English
Published:	2017
Subjects:	RG Gynecology and obstetrics
Online Access:	http://eprints.usm.my/43133/ http://eprints.usm.my/43133/1/Dr._Murtala_Bello_Abubakar-24_pages.pdf

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