Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
Adherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-pro...
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| Format: | Thesis |
| Language: | English |
| Published: |
2010
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| Online Access: | http://eprints.usm.my/42870/ http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf |
| _version_ | 1848879678671028224 |
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| author | Sundaram , Arunkumar |
| author_facet | Sundaram , Arunkumar |
| author_sort | Sundaram , Arunkumar |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Adherence to antihypertensive medications in general is not well documented in
developing countries, and what is known is far from encouraging. Despite the
effectiveness of antihypertensive treatment, medication adherence is often suboptimal in
hypertensive Malaysian population. This retro-prospective cohort study aimed to assess
the medication adherence, and factors affecting this. A cohort of 380 hypertensive
patients was conveniently recruited from the outpatient hypertension clinic at Penang
General Hospital, Malaysia. The Morisky self-report scale revealed that 51.3% patients
(n=195) had poor adherence to prescribed antihypertensive medication. A Semistructured
interview revealed forgetfulness due to a lack of symptoms; poor social
support, medication side effects, and the perception that long-term medication may be
addictive were principal factors of poor adherence to medication. The structural equation
modelling (SEM), which identified the multivariate hypothesized predictors of poor
adherence to medication, showed that a lack of self discipline, aversion towards
medication, and a negative attitude towards medication in general negatively accounted
for 75% of factors affecting medication adherence. |
| first_indexed | 2025-11-15T17:51:03Z |
| format | Thesis |
| id | usm-42870 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T17:51:03Z |
| publishDate | 2010 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-428702019-04-12T05:26:52Z http://eprints.usm.my/42870/ Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr) Sundaram , Arunkumar R5-130.5 General works Adherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-prospective cohort study aimed to assess the medication adherence, and factors affecting this. A cohort of 380 hypertensive patients was conveniently recruited from the outpatient hypertension clinic at Penang General Hospital, Malaysia. The Morisky self-report scale revealed that 51.3% patients (n=195) had poor adherence to prescribed antihypertensive medication. A Semistructured interview revealed forgetfulness due to a lack of symptoms; poor social support, medication side effects, and the perception that long-term medication may be addictive were principal factors of poor adherence to medication. The structural equation modelling (SEM), which identified the multivariate hypothesized predictors of poor adherence to medication, showed that a lack of self discipline, aversion towards medication, and a negative attitude towards medication in general negatively accounted for 75% of factors affecting medication adherence. 2010-06 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf Sundaram , Arunkumar (2010) Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr). Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | R5-130.5 General works Sundaram , Arunkumar Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr) |
| title | Antioxidant Status And The Effect Of
Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In
Spontaneously Hypertensive Rats (Shr)
|
| title_full | Antioxidant Status And The Effect Of
Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In
Spontaneously Hypertensive Rats (Shr)
|
| title_fullStr | Antioxidant Status And The Effect Of
Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In
Spontaneously Hypertensive Rats (Shr)
|
| title_full_unstemmed | Antioxidant Status And The Effect Of
Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In
Spontaneously Hypertensive Rats (Shr)
|
| title_short | Antioxidant Status And The Effect Of
Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In
Spontaneously Hypertensive Rats (Shr)
|
| title_sort | antioxidant status and the effect of
tocotrienol-rich-fraction (trf) supplementation on the antioxidant enzymes and development of hypertension in
spontaneously hypertensive rats (shr) |
| topic | R5-130.5 General works |
| url | http://eprints.usm.my/42870/ http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf |