Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with...
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| Format: | Thesis |
| Language: | English |
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2011
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| Online Access: | http://eprints.usm.my/42494/ http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf |
| _version_ | 1848879575536238592 |
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| author | Karim, Sabiha |
| author_facet | Karim, Sabiha |
| author_sort | Karim, Sabiha |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the
feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with extrusion-spheronisation process in terms of physical characteristics and in-vitro dissolution profile of the developed formulations. The fast release paracetamol pellets were comprised of, microcrystalline
cellulose, lactose, crospovidone and polyvinyl pyrrolidone-K90. |
| first_indexed | 2025-11-15T17:49:25Z |
| format | Thesis |
| id | usm-42494 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T17:49:25Z |
| publishDate | 2011 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-424942019-04-12T05:26:38Z http://eprints.usm.my/42494/ Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation Karim, Sabiha RS1-441 Pharmacy and materia medica Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with extrusion-spheronisation process in terms of physical characteristics and in-vitro dissolution profile of the developed formulations. The fast release paracetamol pellets were comprised of, microcrystalline cellulose, lactose, crospovidone and polyvinyl pyrrolidone-K90. 2011-03 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf Karim, Sabiha (2011) Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Karim, Sabiha Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation |
| title | Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
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| title_full | Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
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| title_fullStr | Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
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| title_full_unstemmed | Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
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| title_short | Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
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| title_sort | design and evaluation of multiparticulate systems prepared using sieving-spheronisation and extrusionspheronisation |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/42494/ http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf |