Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study
Background High grade gliomas (HGGs) are locally invasive and aggressive brain tumors that carry dismal prognosis. Despite the rapidly evolving therapeutic strategies to treat HGGs, Malaysia still failed to demonstrate the expected standard HGGs management. According to National Comprehensive Cance...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2016
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/42422/ http://eprints.usm.my/42422/1/Dr._Ng_Wei_Ping-24_pages.pdf |
| _version_ | 1848879556344152064 |
|---|---|
| author | Ping, Ng Wei |
| author_facet | Ping, Ng Wei |
| author_sort | Ping, Ng Wei |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Background
High grade gliomas (HGGs) are locally invasive and aggressive brain tumors that carry dismal prognosis. Despite the rapidly evolving therapeutic strategies to treat HGGs, Malaysia still failed to demonstrate the expected standard HGGs management. According to National Comprehensive Cancer Network (NCCN) Guideline, the current standard management of HGGs includes maximum safe microsurgery resection followed by chemotherapy and radiotherapy. Complete resection, though increases median survival, is often hindered by the challenge of demonstrating the tumor border reliably. Department of Neurosurgery Hospital Sungai Buloh therefore has adopted fluorescence guided (FG) surgery using 5-aminolevulinic acid (5-ALA) as the first public hospital in Malaysia to overcome this shortcoming since 2010. |
| first_indexed | 2025-11-15T17:49:06Z |
| format | Thesis |
| id | usm-42422 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T17:49:06Z |
| publishDate | 2016 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-424222019-04-21T02:15:53Z http://eprints.usm.my/42422/ Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study Ping, Ng Wei RB Pathology Background High grade gliomas (HGGs) are locally invasive and aggressive brain tumors that carry dismal prognosis. Despite the rapidly evolving therapeutic strategies to treat HGGs, Malaysia still failed to demonstrate the expected standard HGGs management. According to National Comprehensive Cancer Network (NCCN) Guideline, the current standard management of HGGs includes maximum safe microsurgery resection followed by chemotherapy and radiotherapy. Complete resection, though increases median survival, is often hindered by the challenge of demonstrating the tumor border reliably. Department of Neurosurgery Hospital Sungai Buloh therefore has adopted fluorescence guided (FG) surgery using 5-aminolevulinic acid (5-ALA) as the first public hospital in Malaysia to overcome this shortcoming since 2010. 2016 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42422/1/Dr._Ng_Wei_Ping-24_pages.pdf Ping, Ng Wei (2016) Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RB Pathology Ping, Ng Wei Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study |
| title | Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study |
| title_full | Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study |
| title_fullStr | Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study |
| title_full_unstemmed | Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study |
| title_short | Fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study |
| title_sort | fluorescence guided versus conventional surgical resection of high grade glioma : a single centre 7 year comparative effectiveness study |
| topic | RB Pathology |
| url | http://eprints.usm.my/42422/ http://eprints.usm.my/42422/1/Dr._Ng_Wei_Ping-24_pages.pdf |