Immunofenotype mononucleus cell peripheral malaria patients

The absolute number and percentage of various T cell subsets in patients with acute malaria infection was investigate with special reference to the expression of the T activation markers, CD25,HLA-DR and CD38. The absolute number but not the percentage of CD4+(p<0.001) and CD8 (p<0.02) T cell...

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Main Authors: Nor, Norazmi Mohd, Jamaluddin, Normah
Format: Conference or Workshop Item
Language:English
Published: 1999
Subjects:
Online Access:http://eprints.usm.my/42349/
http://eprints.usm.my/42349/1/GP...Immunofenotaip_Sel_Mononukleus_Periferi_Pesakit_Malaria..OCR...pdf
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author Nor, Norazmi Mohd
Jamaluddin, Normah
author_facet Nor, Norazmi Mohd
Jamaluddin, Normah
author_sort Nor, Norazmi Mohd
building USM Institutional Repository
collection Online Access
description The absolute number and percentage of various T cell subsets in patients with acute malaria infection was investigate with special reference to the expression of the T activation markers, CD25,HLA-DR and CD38. The absolute number but not the percentage of CD4+(p<0.001) and CD8 (p<0.02) T cell subsets as well as total B cells (CD19+) (p<0.02) was reduced in these patients. In contrast, the percentage of T cells bearing the gamma-delta (gd) T-cell receptor (TCR) was significantly increased (p<0.02). Although the expression of CD25 on any of the T cell subsets with the normal range, increases in the percentage of CD8+CD38 + (p<0.005) gd+HLA-DR+ (p<0.001) and gd+CD38+ (p<0.005) T cell subsets may be suggestive inter-relationship with the disease the significant of which remains to of their be ascertained.
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format Conference or Workshop Item
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institution Universiti Sains Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T17:48:47Z
publishDate 1999
recordtype eprints
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spelling usm-423492019-02-20T01:11:07Z http://eprints.usm.my/42349/ Immunofenotype mononucleus cell peripheral malaria patients Nor, Norazmi Mohd Jamaluddin, Normah RA643-645 Disease (Communicable and noninfectious) and public health The absolute number and percentage of various T cell subsets in patients with acute malaria infection was investigate with special reference to the expression of the T activation markers, CD25,HLA-DR and CD38. The absolute number but not the percentage of CD4+(p<0.001) and CD8 (p<0.02) T cell subsets as well as total B cells (CD19+) (p<0.02) was reduced in these patients. In contrast, the percentage of T cells bearing the gamma-delta (gd) T-cell receptor (TCR) was significantly increased (p<0.02). Although the expression of CD25 on any of the T cell subsets with the normal range, increases in the percentage of CD8+CD38 + (p<0.005) gd+HLA-DR+ (p<0.001) and gd+CD38+ (p<0.005) T cell subsets may be suggestive inter-relationship with the disease the significant of which remains to of their be ascertained. 1999 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.usm.my/42349/1/GP...Immunofenotaip_Sel_Mononukleus_Periferi_Pesakit_Malaria..OCR...pdf Nor, Norazmi Mohd and Jamaluddin, Normah (1999) Immunofenotype mononucleus cell peripheral malaria patients. In: Immunofenotype mononucleus cell peripheral malaria patients. (Submitted) http://ethesis.usm.my:8080/jspui/handle/123456789/6880
spellingShingle RA643-645 Disease (Communicable and noninfectious) and public health
Nor, Norazmi Mohd
Jamaluddin, Normah
Immunofenotype mononucleus cell peripheral malaria patients
title Immunofenotype mononucleus cell peripheral malaria patients
title_full Immunofenotype mononucleus cell peripheral malaria patients
title_fullStr Immunofenotype mononucleus cell peripheral malaria patients
title_full_unstemmed Immunofenotype mononucleus cell peripheral malaria patients
title_short Immunofenotype mononucleus cell peripheral malaria patients
title_sort immunofenotype mononucleus cell peripheral malaria patients
topic RA643-645 Disease (Communicable and noninfectious) and public health
url http://eprints.usm.my/42349/
http://eprints.usm.my/42349/
http://eprints.usm.my/42349/1/GP...Immunofenotaip_Sel_Mononukleus_Periferi_Pesakit_Malaria..OCR...pdf