Immunofenotype mononucleus cell peripheral malaria patients
The absolute number and percentage of various T cell subsets in patients with acute malaria infection was investigate with special reference to the expression of the T activation markers, CD25,HLA-DR and CD38. The absolute number but not the percentage of CD4+(p<0.001) and CD8 (p<0.02) T cell...
| Main Authors: | , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
1999
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| Subjects: | |
| Online Access: | http://eprints.usm.my/42349/ http://eprints.usm.my/42349/1/GP...Immunofenotaip_Sel_Mononukleus_Periferi_Pesakit_Malaria..OCR...pdf |
| Summary: | The absolute number and percentage of various T cell subsets in patients with acute malaria infection was investigate with special reference to the expression of the T activation markers, CD25,HLA-DR and CD38. The absolute number but not the percentage of CD4+(p<0.001) and CD8 (p<0.02) T cell subsets as well as total B cells (CD19+) (p<0.02) was reduced in these patients. In contrast, the percentage of T cells bearing the gamma-delta (gd) T-cell receptor (TCR) was significantly increased (p<0.02). Although the expression of CD25 on any of the T cell subsets with the normal range, increases in the percentage of CD8+CD38 + (p<0.005) gd+HLA-DR+ (p<0.001) and gd+CD38+ (p<0.005) T cell subsets may be suggestive inter-relationship with the disease the significant of which remains to of their be ascertained. |
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