Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats
Little information exists about the effects of swimming exercise on bone health in ovariectomized animals with estrogen deficiency, which resembles the postmenopausal state and age-related bone loss in humans. This study investigated the effects of swimming exercise on tibia and femur bone mineral...
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Elsevier
2014
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| Online Access: | http://eprints.usm.my/38905/ |
| _version_ | 1848878598410207232 |
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| author | Foong, Kiew Ooi Norsyam, Wan Mohd Ghosh, Asok Kumar Sulaiman, Siti Amrah Chee, Keong Chen Hung, Leung Kim |
| author_facet | Foong, Kiew Ooi Norsyam, Wan Mohd Ghosh, Asok Kumar Sulaiman, Siti Amrah Chee, Keong Chen Hung, Leung Kim |
| author_sort | Foong, Kiew Ooi |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Little information exists about the effects of swimming exercise on bone health in ovariectomized animals with estrogen deficiency, which
resembles the postmenopausal state and age-related bone loss in humans. This study investigated the effects of swimming exercise on tibia and
femur bone mineral density (BMD), geometry, and microstructure in sham and ovariectomized rats. Forty 3-month-old female rats were divided
into four groups: sham operated-sedentary control (Sham-control), sham operated with swimming exercise group (Sham-Swim), ovariectomysedentary
control (OVx-control), and ovariectomy and swimming exercise (OVx-Swim) groups. Swimming sessions were performed by the rats
90 minutes/day for 5 days/week for a total of 8 weeks. At the end of the study, tibial and femoral proximal volumetric total BMD, midshaft
cortical volumetric BMD, cross-sectional area, and cross-sectional moment of inertia (MOI), and bone microstructural properties were measured
for comparison. Data were analyzed using one-way analysis of variance (ANOVA). The Sham-Swim group exhibited significantly ( p < 0.05;
one-way ANOVA) greater values in bone geometry parameters, that is, tibial midshaft cortical area and MOI compared to the Sham-control
group. However, no significant differences were observed in these parameters between the Ovx-Swim and Ovx-control groups. There were
no significant differences in femoral BMD between the Sham-Swim and Sham-control groups. Nevertheless, the Ovx-Swim group elicited
significantly ( p < 0.05; one-way ANOVA) higher femoral proximal total BMD and improved bone microstructure compared to the Ovx-Sham
group. In conclusion, the positive effects of swimming on bone properties in the ovariectomized rats in the present study may suggest that
swimming as a non- or low-weight-bearing exercise may be beneficial for enhancing bone health in the postmenopausal population. |
| first_indexed | 2025-11-15T17:33:53Z |
| format | Article |
| id | usm-38905 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T17:33:53Z |
| publishDate | 2014 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-389052018-02-14T04:07:18Z http://eprints.usm.my/38905/ Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats Foong, Kiew Ooi Norsyam, Wan Mohd Ghosh, Asok Kumar Sulaiman, Siti Amrah Chee, Keong Chen Hung, Leung Kim RM Therapeutics. Pharmacology Little information exists about the effects of swimming exercise on bone health in ovariectomized animals with estrogen deficiency, which resembles the postmenopausal state and age-related bone loss in humans. This study investigated the effects of swimming exercise on tibia and femur bone mineral density (BMD), geometry, and microstructure in sham and ovariectomized rats. Forty 3-month-old female rats were divided into four groups: sham operated-sedentary control (Sham-control), sham operated with swimming exercise group (Sham-Swim), ovariectomysedentary control (OVx-control), and ovariectomy and swimming exercise (OVx-Swim) groups. Swimming sessions were performed by the rats 90 minutes/day for 5 days/week for a total of 8 weeks. At the end of the study, tibial and femoral proximal volumetric total BMD, midshaft cortical volumetric BMD, cross-sectional area, and cross-sectional moment of inertia (MOI), and bone microstructural properties were measured for comparison. Data were analyzed using one-way analysis of variance (ANOVA). The Sham-Swim group exhibited significantly ( p < 0.05; one-way ANOVA) greater values in bone geometry parameters, that is, tibial midshaft cortical area and MOI compared to the Sham-control group. However, no significant differences were observed in these parameters between the Ovx-Swim and Ovx-control groups. There were no significant differences in femoral BMD between the Sham-Swim and Sham-control groups. Nevertheless, the Ovx-Swim group elicited significantly ( p < 0.05; one-way ANOVA) higher femoral proximal total BMD and improved bone microstructure compared to the Ovx-Sham group. In conclusion, the positive effects of swimming on bone properties in the ovariectomized rats in the present study may suggest that swimming as a non- or low-weight-bearing exercise may be beneficial for enhancing bone health in the postmenopausal population. Elsevier 2014-12 Article PeerReviewed Foong, Kiew Ooi and Norsyam, Wan Mohd and Ghosh, Asok Kumar and Sulaiman, Siti Amrah and Chee, Keong Chen and Hung, Leung Kim (2014) Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats. Journal of Exercise Science and Fitness, 12 (2). pp. 80-87. ISSN 1728-869X https://doi.org/10.1016/j.jesf.2014.09.001 |
| spellingShingle | RM Therapeutics. Pharmacology Foong, Kiew Ooi Norsyam, Wan Mohd Ghosh, Asok Kumar Sulaiman, Siti Amrah Chee, Keong Chen Hung, Leung Kim Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats |
| title | Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats |
| title_full | Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats |
| title_fullStr | Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats |
| title_full_unstemmed | Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats |
| title_short | Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats |
| title_sort | effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats |
| topic | RM Therapeutics. Pharmacology |
| url | http://eprints.usm.my/38905/ http://eprints.usm.my/38905/ |