Diffuse unilateral subacute neuroretinitis in a young boy: a case report
We report a case of diffuse unilateral subacute neuroretinitis in a young boy with no clinical visualization of nematode. The diagnosis was made based on clinical findings and detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy presented with progressive blurring...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2012
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| Online Access: | http://eprints.usm.my/38694/ http://eprints.usm.my/38694/1/Diffuse_unilateral_subacute_neuroretinitis_in_a_young_boy_a_case_report.pdf |
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| author | Ng, Guan Fook Abd Aziz, Hayati Raja Azmi, Mohd Noor Ahmad Tajudin, Liza Sharmini Wan Hitam, Wan Hazabbah Embong, Zunaina |
| author_facet | Ng, Guan Fook Abd Aziz, Hayati Raja Azmi, Mohd Noor Ahmad Tajudin, Liza Sharmini Wan Hitam, Wan Hazabbah Embong, Zunaina |
| author_sort | Ng, Guan Fook |
| building | USM Institutional Repository |
| collection | Online Access |
| description | We report a case of diffuse unilateral subacute neuroretinitis in a young boy with
no clinical visualization of nematode. The diagnosis was made based on clinical findings and
detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy
presented with progressive blurring of vision in the left eye for a duration of 1 year. It was
associated with intermittent floaters. Visual acuity in the left eye was 6/45 and improved to 6/24
with pinhole. There was positive relative afferent pupillary defect, impaired color vision, and
presence of red desaturation in the left eye. There were occasional cells in the anterior chamber
with no conjunctiva injection. Posterior segment examination revealed mild-to-moderate
vitritis and generalized pigmentary changes of the retina with attenuated vessels. The optic
disk was slightly hyperemic with mild edema. There was presence of multiple, focal, graywhite
subretinal lesions at the inferior part of the retina. Full blood picture results showed
eosinophilia with detection of Toxocara immunoglobulin G by Western blot test. Investigations
for other infective causes and connective tissue diseases were negative. The diagnosis of diffuse
unilateral subacute neuroretinitis secondary to Toxocara was made based on clinical findings
and laboratory results. He was treated with oral albendazole 400 mg daily for 5 days and oral
prednisolone 1 mg/kg with tapering doses over 6 weeks. At 1 month follow-up, the inflammation
had reduced, and multiple, focal, gray-white subretinal lesions were resolved; however there
was no improvement of vision. |
| first_indexed | 2025-11-15T17:32:58Z |
| format | Article |
| id | usm-38694 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T17:32:58Z |
| publishDate | 2012 |
| publisher | Dove Medical Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-386942018-02-06T00:29:28Z http://eprints.usm.my/38694/ Diffuse unilateral subacute neuroretinitis in a young boy: a case report Ng, Guan Fook Abd Aziz, Hayati Raja Azmi, Mohd Noor Ahmad Tajudin, Liza Sharmini Wan Hitam, Wan Hazabbah Embong, Zunaina RE Ophthalmology We report a case of diffuse unilateral subacute neuroretinitis in a young boy with no clinical visualization of nematode. The diagnosis was made based on clinical findings and detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy presented with progressive blurring of vision in the left eye for a duration of 1 year. It was associated with intermittent floaters. Visual acuity in the left eye was 6/45 and improved to 6/24 with pinhole. There was positive relative afferent pupillary defect, impaired color vision, and presence of red desaturation in the left eye. There were occasional cells in the anterior chamber with no conjunctiva injection. Posterior segment examination revealed mild-to-moderate vitritis and generalized pigmentary changes of the retina with attenuated vessels. The optic disk was slightly hyperemic with mild edema. There was presence of multiple, focal, graywhite subretinal lesions at the inferior part of the retina. Full blood picture results showed eosinophilia with detection of Toxocara immunoglobulin G by Western blot test. Investigations for other infective causes and connective tissue diseases were negative. The diagnosis of diffuse unilateral subacute neuroretinitis secondary to Toxocara was made based on clinical findings and laboratory results. He was treated with oral albendazole 400 mg daily for 5 days and oral prednisolone 1 mg/kg with tapering doses over 6 weeks. At 1 month follow-up, the inflammation had reduced, and multiple, focal, gray-white subretinal lesions were resolved; however there was no improvement of vision. Dove Medical Press 2012 Article PeerReviewed application/pdf en http://eprints.usm.my/38694/1/Diffuse_unilateral_subacute_neuroretinitis_in_a_young_boy_a_case_report.pdf Ng, Guan Fook and Abd Aziz, Hayati and Raja Azmi, Mohd Noor and Ahmad Tajudin, Liza Sharmini and Wan Hitam, Wan Hazabbah and Embong, Zunaina (2012) Diffuse unilateral subacute neuroretinitis in a young boy: a case report. Clinical Ophthalmology, 2012 (6). pp. 487-490. ISSN 1177-5467 https://doi.org/10.2147/OPTH.S29806 |
| spellingShingle | RE Ophthalmology Ng, Guan Fook Abd Aziz, Hayati Raja Azmi, Mohd Noor Ahmad Tajudin, Liza Sharmini Wan Hitam, Wan Hazabbah Embong, Zunaina Diffuse unilateral subacute neuroretinitis in a young boy: a case report |
| title | Diffuse unilateral subacute neuroretinitis in a young boy: a case report |
| title_full | Diffuse unilateral subacute neuroretinitis in a young boy: a case report |
| title_fullStr | Diffuse unilateral subacute neuroretinitis in a young boy: a case report |
| title_full_unstemmed | Diffuse unilateral subacute neuroretinitis in a young boy: a case report |
| title_short | Diffuse unilateral subacute neuroretinitis in a young boy: a case report |
| title_sort | diffuse unilateral subacute neuroretinitis in a young boy: a case report |
| topic | RE Ophthalmology |
| url | http://eprints.usm.my/38694/ http://eprints.usm.my/38694/ http://eprints.usm.my/38694/1/Diffuse_unilateral_subacute_neuroretinitis_in_a_young_boy_a_case_report.pdf |