Development of an Antigen-DNAzyme Based Probe for a Direct Antibody-Antigen Assay Using the Intrinsic DNAzyme Activity of a Daunomycin Aptamer

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Development of an Antigen-DNAzyme Based Probe for a Direct Antibody-Antigen Assay Using the Intrinsic DNAzyme Activity of a Daunomycin Aptamer

G-Quadruplex (G-4) structures are formed when G-rich DNA sequences fold into intra- or intermolecular four-stranded structures in the presence of metal ions. G-4-hemin complexes are often effective peroxidase-mimicking DNAzymes that are applied in many detection systems. This work reports the applic...

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Bibliographic Details
Main Authors:	Omar, Noorsharmimi, Loh, Qiuting, Gee, Jun Tye, Yee, Siew Choong, Noordin, Rahmah, Jörn, Glökler, Lim, Theam Soon
Format:	Article
Language:	English
Published:	MDPI 2014
Subjects:	R735-854 Medical education. Medical schools. Research
Online Access:	http://eprints.usm.my/38675/ http://eprints.usm.my/38675/1/Development_of_an_Antigen-DNAzyme_Based_Probe_for_a_Direct_Antibody-Antigen.pdf

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