Cissus quadrangularis inhibits IL -1β induced inflammatory responses on chondrocytes and alleviates bone deterioration in osteotomized rats via p38 MAPK signaling

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Cissus quadrangularis inhibits IL -1β induced inflammatory responses on chondrocytes and alleviates bone deterioration in osteotomized rats via p38 MAPK signaling

Introduction: Inflammatory mediators are key players in the pathogenesis of osteoarthritis (OA) and bone destruction. Conventional drugs suppress symptomatic activity and have no therapeutic influence on disease. Cissus quadrangularis and Withania somnifera are widely used for the treatment of bone...

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Bibliographic Details
Main Authors:	Kanwar, Jagat R, Samarasinghe, Rasika M, Kumar, Kuldeep, Arya, Ramesh, Sharma, Sanjeev, Zhou, Shu Feng, Sasidharan, Sreenivasan, Kanwar, Rupinder K
Format:	Article
Language:	English
Published:	Dove Medical Press 2015
Subjects:	R735-854 Medical education. Medical schools. Research
Online Access:	http://eprints.usm.my/38450/ http://eprints.usm.my/38450/1/Cissus_quadrangularis_inhibits_IL-1%CE%B2_induced_inflammatory_responses_on_chondrocytes.pdf

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