Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review

Curcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad range of pharmacological properties at relatively nontoxic doses. Curcumin is found to be effective against Staphylococcus aureus (S. aure...

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Main Authors: Teow , Sin Yeang, Liew, Kitson, Ali, Syed A., Khoo, Alan Soo Beng, Peh, Suat Cheng
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2016
Subjects:
Online Access:http://eprints.usm.my/38327/
http://eprints.usm.my/38327/1/Antibacterial_Action_of_Curcumin_against_Staphylococcus_aureus_A_Brief_Review.pdf
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author Teow , Sin Yeang
Liew, Kitson
Ali, Syed A.
Khoo, Alan Soo Beng
Peh, Suat Cheng
author_facet Teow , Sin Yeang
Liew, Kitson
Ali, Syed A.
Khoo, Alan Soo Beng
Peh, Suat Cheng
author_sort Teow , Sin Yeang
building USM Institutional Repository
collection Online Access
description Curcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad range of pharmacological properties at relatively nontoxic doses. Curcumin is found to be effective against Staphylococcus aureus (S. aureus). As demonstrated by in vitro experiment, curcumin exerts even more potent effects when used in combination with various other antibacterial agents. Hence, curcumin which is a natural product derived fromplant is believed to have profoundmedicinal benefits and could be potentially developed into a naturally derived antibiotic in the future. However, there are several noteworthy challenges in the development of curcumin as a medicine. S. aureus infections, particularly those caused by themultidrug-resistant strains, have emerged as a global health issue and urgent action is needed.This review focuses on the antibacterial activities of curcumin against both methicillin-sensitive S. aureus (MSSA) and methicillinresistant S. aureus (MRSA). We also attempt to highlight the potential challenges in the effort of developing curcumin into a therapeutic antibacterial agent.
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spelling usm-383272018-01-10T06:06:52Z http://eprints.usm.my/38327/ Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review Teow , Sin Yeang Liew, Kitson Ali, Syed A. Khoo, Alan Soo Beng Peh, Suat Cheng RK1-715 Dentistry Curcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad range of pharmacological properties at relatively nontoxic doses. Curcumin is found to be effective against Staphylococcus aureus (S. aureus). As demonstrated by in vitro experiment, curcumin exerts even more potent effects when used in combination with various other antibacterial agents. Hence, curcumin which is a natural product derived fromplant is believed to have profoundmedicinal benefits and could be potentially developed into a naturally derived antibiotic in the future. However, there are several noteworthy challenges in the development of curcumin as a medicine. S. aureus infections, particularly those caused by themultidrug-resistant strains, have emerged as a global health issue and urgent action is needed.This review focuses on the antibacterial activities of curcumin against both methicillin-sensitive S. aureus (MSSA) and methicillinresistant S. aureus (MRSA). We also attempt to highlight the potential challenges in the effort of developing curcumin into a therapeutic antibacterial agent. Hindawi Publishing Corporation 2016 Article PeerReviewed application/pdf en http://eprints.usm.my/38327/1/Antibacterial_Action_of_Curcumin_against_Staphylococcus_aureus_A_Brief_Review.pdf Teow , Sin Yeang and Liew, Kitson and Ali, Syed A. and Khoo, Alan Soo Beng and Peh, Suat Cheng (2016) Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review. Journal of Tropical Medicine, 2016 (285304). pp. 1-10. ISSN 1687-9686 http://dx.doi.org/10.1155/2016/2853045
spellingShingle RK1-715 Dentistry
Teow , Sin Yeang
Liew, Kitson
Ali, Syed A.
Khoo, Alan Soo Beng
Peh, Suat Cheng
Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review
title Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review
title_full Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review
title_fullStr Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review
title_full_unstemmed Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review
title_short Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review
title_sort antibacterial action of curcumin against staphylococcus aureus: a brief review
topic RK1-715 Dentistry
url http://eprints.usm.my/38327/
http://eprints.usm.my/38327/
http://eprints.usm.my/38327/1/Antibacterial_Action_of_Curcumin_against_Staphylococcus_aureus_A_Brief_Review.pdf