An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report

We report a 33-year-old Malay woman presented with acute left dense hemiparesis and an NIHSS score of 11/15. Computed tomography (CT) scan brain showed a massive right middle cerebral artery (MCA) territory infarct. The right internal carotid artery (ICA) and right proximal MCA were shown occluded...

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Main Authors: Yeong, Yeh Lee, Bhaskar, Shalini
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2011
Subjects:
Online Access:http://eprints.usm.my/38315/
http://eprints.usm.my/38315/1/An_Unusual_Association_between_Unilateral_Intracranial_Vessels.pdf
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author Yeong, Yeh Lee
Bhaskar, Shalini
author_facet Yeong, Yeh Lee
Bhaskar, Shalini
author_sort Yeong, Yeh Lee
building USM Institutional Repository
collection Online Access
description We report a 33-year-old Malay woman presented with acute left dense hemiparesis and an NIHSS score of 11/15. Computed tomography (CT) scan brain showed a massive right middle cerebral artery (MCA) territory infarct. The right internal carotid artery (ICA) and right proximal MCA were shown occluded from digital substraction angiography (DSA). Carotid dissection, carotid canal anomaly, and intercavernous communication were systematically ruled out. She had no risk factors for atherosclerosis. The connective tissue screening and thrombophilic markers were negative. However, she was anaemic on admission and subsequent investigations revealed that she had alpha-thalassemia and iron deficiency anaemia. The right ICA remained occluded from a repeat CT cerebral angiogram after one year, but otherwise she was neurologically stable. This case illustrates an unusual association between intracranial vessel occlusion with iron deficiency anaemia and alpha-thalassemia trait.
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spelling usm-383152018-01-09T07:59:04Z http://eprints.usm.my/38315/ An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report Yeong, Yeh Lee Bhaskar, Shalini R5-920 Medicine (General) We report a 33-year-old Malay woman presented with acute left dense hemiparesis and an NIHSS score of 11/15. Computed tomography (CT) scan brain showed a massive right middle cerebral artery (MCA) territory infarct. The right internal carotid artery (ICA) and right proximal MCA were shown occluded from digital substraction angiography (DSA). Carotid dissection, carotid canal anomaly, and intercavernous communication were systematically ruled out. She had no risk factors for atherosclerosis. The connective tissue screening and thrombophilic markers were negative. However, she was anaemic on admission and subsequent investigations revealed that she had alpha-thalassemia and iron deficiency anaemia. The right ICA remained occluded from a repeat CT cerebral angiogram after one year, but otherwise she was neurologically stable. This case illustrates an unusual association between intracranial vessel occlusion with iron deficiency anaemia and alpha-thalassemia trait. Hindawi Publishing Corporation 2011 Article PeerReviewed application/pdf en http://eprints.usm.my/38315/1/An_Unusual_Association_between_Unilateral_Intracranial_Vessels.pdf Yeong, Yeh Lee and Bhaskar, Shalini (2011) An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report. Case Reports in Medicine, 2011 (271560). pp. 1-4. ISSN 1687-9627 https://doi.org/10.1155/2011/271560
spellingShingle R5-920 Medicine (General)
Yeong, Yeh Lee
Bhaskar, Shalini
An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report
title An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report
title_full An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report
title_fullStr An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report
title_full_unstemmed An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report
title_short An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report
title_sort unusual association between unilateral intracranial vessels occlusion with iron deficiency anaemia and alpha-thalassemia trait: a case report
topic R5-920 Medicine (General)
url http://eprints.usm.my/38315/
http://eprints.usm.my/38315/
http://eprints.usm.my/38315/1/An_Unusual_Association_between_Unilateral_Intracranial_Vessels.pdf