The role of REST and HDAC2
in epigenetic dysregulation of Nav1.5
and nNav1.5 expression in breast cancer

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The role of REST and HDAC2 in epigenetic dysregulation of Nav1.5 and nNav1.5 expression in breast cancer

Background: Increased expression of voltage-gated sodium channels (VGSCs) have been implicated with strong metastatic potential of human breast cancer in vitro and in vivo where the main culprits are cardiac isoform Nav1.5 and its ‘neonatal’ splice variant, nNav1.5. Several factors have been assoc...

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Bibliographic Details
Main Authors:	Kamarulzaman, Nur Sabrina, Dewadas, Hemaniswarri Dewi, Chiuan, Yee Leow, Yaacob, Nik Soriani, Mokhtar, Noor Fatmawati
Format:	Article
Language:	English
Published:	BioMed Central 2017
Subjects:	RD520-599.5 Surgery by region, system, or organ
Online Access:	http://eprints.usm.my/38047/ http://eprints.usm.my/38047/1/4th_paper_2017.pdf

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