A masquerader: A report of rapid progressive primary intraocular lymphoma

Primary intraocular lymphoma (PIOL) is an uncommon subset of primary central nervous system lymphoma (PCNSL). We report a rapid progressive of this disease in a 73 years old lady who presented with one year history of left eye floaters, associated with deterioration of left vision. Examination revea...

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Main Authors: Mat Abu, Siti Hajar, Hashim, Hanizasurana, Aziz, Roslin Azni, Ngah, Norfariza, Hussein, Adil, Othman, Noriah
Format: Article
Published: Elsevier 2013
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Online Access:http://eprints.usm.my/38036/
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author Mat Abu, Siti Hajar
Hashim, Hanizasurana
Aziz, Roslin Azni
Ngah, Norfariza
Hussein, Adil
Othman, Noriah
author_facet Mat Abu, Siti Hajar
Hashim, Hanizasurana
Aziz, Roslin Azni
Ngah, Norfariza
Hussein, Adil
Othman, Noriah
author_sort Mat Abu, Siti Hajar
building USM Institutional Repository
collection Online Access
description Primary intraocular lymphoma (PIOL) is an uncommon subset of primary central nervous system lymphoma (PCNSL). We report a rapid progressive of this disease in a 73 years old lady who presented with one year history of left eye floaters, associated with deterioration of left vision. Examination revealed left eye vitritis and typical vitreous clumps. Left vitrectomy and vitreous biopsy was performed with result showed few singly dispersed atypical lymphoid cells. She was diagnosed to have Primary Intraocular lymphoma and was started on intravitreal methotrexate. Initially she responded well but later the tumour spread to liver, breast and brain within a year. She finally succumbed to the disease. High index of suspicion of PIOL is mandatory in all elderly patients presenting with panuveitis. Co-management with the Neurologist is vital in the continuous management of these patients in view of the high rate of mortality.
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spelling usm-380362017-12-20T07:53:29Z http://eprints.usm.my/38036/ A masquerader: A report of rapid progressive primary intraocular lymphoma Mat Abu, Siti Hajar Hashim, Hanizasurana Aziz, Roslin Azni Ngah, Norfariza Hussein, Adil Othman, Noriah RE Ophthalmology Primary intraocular lymphoma (PIOL) is an uncommon subset of primary central nervous system lymphoma (PCNSL). We report a rapid progressive of this disease in a 73 years old lady who presented with one year history of left eye floaters, associated with deterioration of left vision. Examination revealed left eye vitritis and typical vitreous clumps. Left vitrectomy and vitreous biopsy was performed with result showed few singly dispersed atypical lymphoid cells. She was diagnosed to have Primary Intraocular lymphoma and was started on intravitreal methotrexate. Initially she responded well but later the tumour spread to liver, breast and brain within a year. She finally succumbed to the disease. High index of suspicion of PIOL is mandatory in all elderly patients presenting with panuveitis. Co-management with the Neurologist is vital in the continuous management of these patients in view of the high rate of mortality. Elsevier 2013 Article PeerReviewed Mat Abu, Siti Hajar and Hashim, Hanizasurana and Aziz, Roslin Azni and Ngah, Norfariza and Hussein, Adil and Othman, Noriah (2013) A masquerader: A report of rapid progressive primary intraocular lymphoma. Journal of Acute Disease , 2 (1). pp. 76-78. ISSN 2221-6189 https://doi.org/10.1016/S2221-6189(13)60102-X
spellingShingle RE Ophthalmology
Mat Abu, Siti Hajar
Hashim, Hanizasurana
Aziz, Roslin Azni
Ngah, Norfariza
Hussein, Adil
Othman, Noriah
A masquerader: A report of rapid progressive primary intraocular lymphoma
title A masquerader: A report of rapid progressive primary intraocular lymphoma
title_full A masquerader: A report of rapid progressive primary intraocular lymphoma
title_fullStr A masquerader: A report of rapid progressive primary intraocular lymphoma
title_full_unstemmed A masquerader: A report of rapid progressive primary intraocular lymphoma
title_short A masquerader: A report of rapid progressive primary intraocular lymphoma
title_sort masquerader: a report of rapid progressive primary intraocular lymphoma
topic RE Ophthalmology
url http://eprints.usm.my/38036/
http://eprints.usm.my/38036/