Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients
Aims: Health-Related Quality of Life (HRQoL) has been increasing attention in health outcome studies. Factors that individually influence HRQoL, diabetes self-care behaviors, and medication adherence have been widely investigated; however, most previous studies have not tested an integrated associ...
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| Format: | Article |
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Elsevier
2017
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| Online Access: | http://eprints.usm.my/36946/ |
| _version_ | 1848878053477842944 |
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| author | Jannoo, Zeinab Yap, Bee Wah Mohd Lazim, Alias Hassali, Mohamed Azmi |
| author_facet | Jannoo, Zeinab Yap, Bee Wah Mohd Lazim, Alias Hassali, Mohamed Azmi |
| author_sort | Jannoo, Zeinab |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Aims: Health-Related Quality of Life (HRQoL) has been increasing attention in health outcome studies.
Factors that individually influence HRQoL, diabetes self-care behaviors, and medication adherence have
been widely investigated; however, most previous studies have not tested an integrated association
between multiple health outcomes. The purpose of this study was to formulate a hypothetical structural
equation model linking HRQoL, diabetes distress, diabetes self-care activities, medication adherence and
diabetes-dependent QoL in patients with Type 2 Diabetes Mellitus (T2DM).
Methods: A cross-sectional study design was employed, and 497 patients with T2DM were recruited from
outpatient clinics in three public hospitals and one government clinic. The patients completed a series of
questionnaires. The hypothetical model was tested using Structural Equation Modeling (SEM) analysis.
Results: The values of the multiple fit indices indicated that the proposed model provided a good fit to the
data. SEM results showed that medication adherence (MMAS) had a significant direct effect on diabetes
distress (PAID) (Beta = -0.20). The self-care activities (SDSCA) construct was significantly related to PAID
(Beta = -0.24). SDSCA was found to have a significant relationship with HRQoL (SF-36) (Beta = 0.11).
Additionally, diabetes distress had a significant effect (Beta = -0.11) on HRQoL of patients. Finally,
ADDQoL had a significant effect on HRQoL (Beta = 0.12).
Conclusions: The various health outcome indicators such as self-care behaviors, diabetes distress, medication
adherence and diabetes-dependent QoL need to be considered in clinical practice for enhancing HRQoL in those patients. |
| first_indexed | 2025-11-15T17:25:13Z |
| format | Article |
| id | usm-36946 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T17:25:13Z |
| publishDate | 2017 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-369462017-10-05T04:12:01Z http://eprints.usm.my/36946/ Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients Jannoo, Zeinab Yap, Bee Wah Mohd Lazim, Alias Hassali, Mohamed Azmi RS1-441 Pharmacy and materia medica Aims: Health-Related Quality of Life (HRQoL) has been increasing attention in health outcome studies. Factors that individually influence HRQoL, diabetes self-care behaviors, and medication adherence have been widely investigated; however, most previous studies have not tested an integrated association between multiple health outcomes. The purpose of this study was to formulate a hypothetical structural equation model linking HRQoL, diabetes distress, diabetes self-care activities, medication adherence and diabetes-dependent QoL in patients with Type 2 Diabetes Mellitus (T2DM). Methods: A cross-sectional study design was employed, and 497 patients with T2DM were recruited from outpatient clinics in three public hospitals and one government clinic. The patients completed a series of questionnaires. The hypothetical model was tested using Structural Equation Modeling (SEM) analysis. Results: The values of the multiple fit indices indicated that the proposed model provided a good fit to the data. SEM results showed that medication adherence (MMAS) had a significant direct effect on diabetes distress (PAID) (Beta = -0.20). The self-care activities (SDSCA) construct was significantly related to PAID (Beta = -0.24). SDSCA was found to have a significant relationship with HRQoL (SF-36) (Beta = 0.11). Additionally, diabetes distress had a significant effect (Beta = -0.11) on HRQoL of patients. Finally, ADDQoL had a significant effect on HRQoL (Beta = 0.12). Conclusions: The various health outcome indicators such as self-care behaviors, diabetes distress, medication adherence and diabetes-dependent QoL need to be considered in clinical practice for enhancing HRQoL in those patients. Elsevier 2017-09 Article PeerReviewed Jannoo, Zeinab and Yap, Bee Wah and Mohd Lazim, Alias and Hassali, Mohamed Azmi (2017) Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients. Journal of Clinical and Translational Endocrinology, 9. pp. 48-54. ISSN 2214-6237 http://dx.doi.org/10.1016/j.jcte.2017.07.003 |
| spellingShingle | RS1-441 Pharmacy and materia medica Jannoo, Zeinab Yap, Bee Wah Mohd Lazim, Alias Hassali, Mohamed Azmi Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients |
| title | Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients |
| title_full | Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients |
| title_fullStr | Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients |
| title_full_unstemmed | Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients |
| title_short | Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients |
| title_sort | examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/36946/ http://eprints.usm.my/36946/ |