Evaluation of Medication Use in Malaysian Predialysis Patients
Chronic kidney disease (CKD) patients suffer from multiple comorbidities and complications as a cause or consequence of kidney disease. Information regarding medicationprescribing patterns in predialysis patients is sparse. We conducted a retrospective study to evaluate the medication prescriptio...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Medknow Publications
2017
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| Subjects: | |
| Online Access: | http://eprints.usm.my/36928/ http://eprints.usm.my/36928/1/%28Evaluation_of_medication_use%29_SaudiJKidneyDisTranspl283517-7557673_205936.pdf |
| Summary: | Chronic kidney disease (CKD) patients suffer from multiple comorbidities and
complications as a cause or consequence of kidney disease. Information regarding medicationprescribing
patterns in predialysis patients is sparse. We conducted a retrospective study to
evaluate the medication prescription patterns among predialysis patients. Medical records (both
paper based and computerized) of patients at CKD Resource Centre, Hospital Universiti Sains
Malaysia, were reviewed. A total of 615 eligible cases were included in the study. The mean
number of medications prescribed per patient was 8.22 ± 2.81, and medication use was correlated
to the renal function (stage 3a < stage 3b < stage 4 < stage 5; P <0.001). The top three prescribed
medication groups were found to be lipid-lowering agents, calcium channel blockers, and
antiplatelet agents. Some medication classes such as nonaluminum/noncalcium phosphate
binders, erythropoietin-stimulating agents, and renin-angiotensin-aldosterone system blockers,
particularly in advanced stage, were found to be underutilized. In conclusion, predialysis patients
are prescribed a large number of medications. Our findings highlight the need for assessing the
impact of current medication-prescribing patterns on morbidity and mortality rates in Malaysian
predialysis population. |
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