Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent.

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Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent.

Gemcitabine remains the standard treatment for pancreatic cancer. although most patients acquire resistance to the therapy. Up-regulated in pancreatic cancer. SIRTI is involved in tumorigenesis and drug resistance, However the mechanism through which SIRTl regulates drug sensitivity in cancer cells...

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Bibliographic Details
Main Author:	Oon , Chern Ein
Format:	Monograph
Published:	Universiti Sains Malaysia 2016
Subjects:	R735-854 Medical education. Medical schools. Research
Online Access:	http://eprints.usm.my/36903/

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