3,5-Bis(arylidene)-4-piperidonesaspotential dengue proteaseinhibitors
Dengue isaseveremosquito-borneviralinfectioncausinghalfamilliondeathsannually. Dengue virusNS2B/NS3proteaseisavalidatedtargetforanti-denguedrugdesign.Aseriesofhitherto unreported 3,5-bis(arylidene)-4-piperidonesanalogues 4a–4j were synthesizedandscreened in silico against DENV2NS2B/NS3proteasetoe...
| Main Authors: | Osman, Hasnah, Idris, Nor Hashima, Kamarulzaman, Ezatul Ezleen, A.Wahab, Habibah, Hassan, Mohd. Zaheen |
|---|---|
| Format: | Article |
| Published: |
Elsevier
2017
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| Subjects: | |
| Online Access: | http://eprints.usm.my/36660/ |
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