Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3

Background: A 2-y school milk intervention trial showed that 330 mL of a dietary milk supplement (fortified with calcium alone or with both calcium and vitamin D) enhanced the growth and bone mineral accretion of Chinese girls aged 10 y at baseline. Girls who received milk fortified with both ca...

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Main Authors: Kun, Zhu, Qian, Zhang, Leng, Huat Foo
Format: Article
Published: American Society for Nutrition 2006
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Online Access:http://eprints.usm.my/36276/
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author Kun, Zhu
Qian, Zhang
Leng, Huat Foo
author_facet Kun, Zhu
Qian, Zhang
Leng, Huat Foo
author_sort Kun, Zhu
building USM Institutional Repository
collection Online Access
description Background: A 2-y school milk intervention trial showed that 330 mL of a dietary milk supplement (fortified with calcium alone or with both calcium and vitamin D) enhanced the growth and bone mineral accretion of Chinese girls aged 10 y at baseline. Girls who received milk fortified with both calcium and vitamin D also had better vitamin D status than did girls who received nothing or girls who received milk fortified only with calcium. Objective: The aim was to evaluate whether these effects were sustained 3 y after supplement withdrawal. Design: Anthropometric measures and dietary intake were reassessed in 501 of the 698 girls whose data had been studied at the end of the intervention. As in the intervention phase, total-body bone mineral content and bone mineral density and serum 25-hydroxyvitamin D concentrations were measured in half of these subjects. Results: At follow-up,99%of girls had reached menarche, at a mean (SD) menarcheal age of 12.11.1 y. No significant differences in the timing of menarche were observed between the 3 groups (P 0.6). No significant differences in the changes of total-body bone mineral content and bone mineral density since baseline were observed between the groups. The group receiving calcium-fortified milk had significantly greater gains in sitting height (0.9 0.3%; P 0.02) than did the control group. The group that received calcium- and vitamin D–fortified milk had 17.16.7% lower serum 25-hydroxyvitaminDconcentrations than did the control group (P 0.04), but the difference was attenuated by additional adjustment for physical activity level (14.2 6.7%; P 0.08). Conclusion: Milk supplementation during early puberty does not have long-lasting effects on bone mineral accretion.
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spelling usm-362762017-11-07T10:30:19Z http://eprints.usm.my/36276/ Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3 Kun, Zhu Qian, Zhang Leng, Huat Foo RA0421 Public health. Hygiene. Preventive Medicine TX341-641 Nutrition. Foods and food supply Background: A 2-y school milk intervention trial showed that 330 mL of a dietary milk supplement (fortified with calcium alone or with both calcium and vitamin D) enhanced the growth and bone mineral accretion of Chinese girls aged 10 y at baseline. Girls who received milk fortified with both calcium and vitamin D also had better vitamin D status than did girls who received nothing or girls who received milk fortified only with calcium. Objective: The aim was to evaluate whether these effects were sustained 3 y after supplement withdrawal. Design: Anthropometric measures and dietary intake were reassessed in 501 of the 698 girls whose data had been studied at the end of the intervention. As in the intervention phase, total-body bone mineral content and bone mineral density and serum 25-hydroxyvitamin D concentrations were measured in half of these subjects. Results: At follow-up,99%of girls had reached menarche, at a mean (SD) menarcheal age of 12.11.1 y. No significant differences in the timing of menarche were observed between the 3 groups (P 0.6). No significant differences in the changes of total-body bone mineral content and bone mineral density since baseline were observed between the groups. The group receiving calcium-fortified milk had significantly greater gains in sitting height (0.9 0.3%; P 0.02) than did the control group. The group that received calcium- and vitamin D–fortified milk had 17.16.7% lower serum 25-hydroxyvitaminDconcentrations than did the control group (P 0.04), but the difference was attenuated by additional adjustment for physical activity level (14.2 6.7%; P 0.08). Conclusion: Milk supplementation during early puberty does not have long-lasting effects on bone mineral accretion. American Society for Nutrition 2006-03 Article PeerReviewed Kun, Zhu and Qian, Zhang and Leng, Huat Foo (2006) Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3. The American Journal of Clinical Nutrition, 83 (3). pp. 714-721. ISSN 1938-3207 http://ajcn.nutrition.org/content/83/3/714.full
spellingShingle RA0421 Public health. Hygiene. Preventive Medicine
TX341-641 Nutrition. Foods and food supply
Kun, Zhu
Qian, Zhang
Leng, Huat Foo
Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3
title Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3
title_full Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3
title_fullStr Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3
title_full_unstemmed Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3
title_short Growth, bone mass, and vitamin D status of Chinese adolescent girls 3 y after withdrawal of milk supplementation1–3
title_sort growth, bone mass, and vitamin d status of chinese adolescent girls 3 y after withdrawal of milk supplementation1–3
topic RA0421 Public health. Hygiene. Preventive Medicine
TX341-641 Nutrition. Foods and food supply
url http://eprints.usm.my/36276/
http://eprints.usm.my/36276/