Studying the role of periplasmic chaperones in Fab presentation on phage surface.
In phage display technology, antibodies presented on phage particles are often a smaller variant of the antibody molecule. The Fab format consists of a pair of heavy chain and light chain that is linked together via a disulphide bridge. The low presentation efficiency of Fab (fragment antigen bindin...
| Main Author: | |
|---|---|
| Format: | Monograph |
| Published: |
Universiti Sains Malaysia
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/32560/ |
| _version_ | 1848876843774509056 |
|---|---|
| author | Lim , Theam Soon |
| author_facet | Lim , Theam Soon |
| author_sort | Lim , Theam Soon |
| building | USM Institutional Repository |
| collection | Online Access |
| description | In phage display technology, antibodies presented on phage particles are often a smaller variant of the antibody molecule. The Fab format consists of a pair of heavy chain and light chain that is linked together via a disulphide bridge. The low presentation efficiency of Fab (fragment antigen binding) fragments during phage display is largely due to the complexity of disulphide bond formation |
| first_indexed | 2025-11-15T17:06:00Z |
| format | Monograph |
| id | usm-32560 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T17:06:00Z |
| publisher | Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-325602017-08-14T06:43:22Z http://eprints.usm.my/32560/ Studying the role of periplasmic chaperones in Fab presentation on phage surface. Lim , Theam Soon R735-854 Medical education. Medical schools. Research In phage display technology, antibodies presented on phage particles are often a smaller variant of the antibody molecule. The Fab format consists of a pair of heavy chain and light chain that is linked together via a disulphide bridge. The low presentation efficiency of Fab (fragment antigen binding) fragments during phage display is largely due to the complexity of disulphide bond formation Universiti Sains Malaysia Monograph NonPeerReviewed Lim , Theam Soon Studying the role of periplasmic chaperones in Fab presentation on phage surface. Project Report. Universiti Sains Malaysia. (Submitted) |
| spellingShingle | R735-854 Medical education. Medical schools. Research Lim , Theam Soon Studying the role of periplasmic chaperones in Fab presentation on phage surface. |
| title | Studying the role of periplasmic chaperones in Fab presentation on phage surface. |
| title_full | Studying the role of periplasmic chaperones in Fab presentation on phage surface. |
| title_fullStr | Studying the role of periplasmic chaperones in Fab presentation on phage surface. |
| title_full_unstemmed | Studying the role of periplasmic chaperones in Fab presentation on phage surface. |
| title_short | Studying the role of periplasmic chaperones in Fab presentation on phage surface. |
| title_sort | studying the role of periplasmic chaperones in fab presentation on phage surface. |
| topic | R735-854 Medical education. Medical schools. Research |
| url | http://eprints.usm.my/32560/ |