Molecular Cloning, Expression, And Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery
Glutation-S-transferase (GSTs) adalah sekumpulan enzim detoksifikasi. Plasmodium falciparum mempunyai isoform tunggal GST (PfGST) yang terlibat dalam bagi detoksifikasi heme. The Glutathione-S-transferases (GSTs) are group of detoxification enzymes. Plasmodium falciparum has a single isoform o...
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| Format: | Thesis |
| Language: | English |
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2015
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| Online Access: | http://eprints.usm.my/30219/ http://eprints.usm.my/30219/1/PhD_thesis_Mohammed_Nooraldeen_Mahmod_march_2015.pdf |
| _version_ | 1848876315602583552 |
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| author | Al-Qattan, Mohammed Nooraldeen Mahmod |
| author_facet | Al-Qattan, Mohammed Nooraldeen Mahmod |
| author_sort | Al-Qattan, Mohammed Nooraldeen Mahmod |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Glutation-S-transferase (GSTs) adalah sekumpulan enzim detoksifikasi. Plasmodium
falciparum mempunyai isoform tunggal GST (PfGST) yang terlibat dalam bagi
detoksifikasi heme.
The Glutathione-S-transferases (GSTs) are group of detoxification enzymes.
Plasmodium falciparum has a single isoform of GST (PfGST) that involves in heme
detoxification. While other GSTs isoforms from human (hGSTP1) and mouse
(mGSTM1) are involved in apoptotic stress kinase pathway and mediate cancer cell
resistance to chemotherapy. |
| first_indexed | 2025-11-15T16:57:36Z |
| format | Thesis |
| id | usm-30219 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T16:57:36Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-302192019-04-12T05:25:47Z http://eprints.usm.my/30219/ Molecular Cloning, Expression, And Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery Al-Qattan, Mohammed Nooraldeen Mahmod QH1 Natural history (General - Including nature conservation, geographical distribution) Glutation-S-transferase (GSTs) adalah sekumpulan enzim detoksifikasi. Plasmodium falciparum mempunyai isoform tunggal GST (PfGST) yang terlibat dalam bagi detoksifikasi heme. The Glutathione-S-transferases (GSTs) are group of detoxification enzymes. Plasmodium falciparum has a single isoform of GST (PfGST) that involves in heme detoxification. While other GSTs isoforms from human (hGSTP1) and mouse (mGSTM1) are involved in apoptotic stress kinase pathway and mediate cancer cell resistance to chemotherapy. 2015-03 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/30219/1/PhD_thesis_Mohammed_Nooraldeen_Mahmod_march_2015.pdf Al-Qattan, Mohammed Nooraldeen Mahmod (2015) Molecular Cloning, Expression, And Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | QH1 Natural history (General - Including nature conservation, geographical distribution) Al-Qattan, Mohammed Nooraldeen Mahmod Molecular Cloning, Expression, And Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery |
| title | Molecular Cloning, Expression, And
Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery |
| title_full | Molecular Cloning, Expression, And
Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery |
| title_fullStr | Molecular Cloning, Expression, And
Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery |
| title_full_unstemmed | Molecular Cloning, Expression, And
Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery |
| title_short | Molecular Cloning, Expression, And
Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery |
| title_sort | molecular cloning, expression, and
characterization of glutathione-stransferase as a novel target in antimalarial drug design and discovery |
| topic | QH1 Natural history (General - Including nature conservation, geographical distribution) |
| url | http://eprints.usm.my/30219/ http://eprints.usm.my/30219/1/PhD_thesis_Mohammed_Nooraldeen_Mahmod_march_2015.pdf |