Mitochondrial redox modulation of NLRP3 inflammasome in
differentiated THP-1 cells

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Mitochondrial redox modulation of NLRP3 inflammasome in differentiated THP-1 cells

Introduction: Innate host defence against pathogen required NLRP3 inflammasome activation. Two steps of inflammasome complex activation are identified: Signal 1 or priming (expression of NLRP3 protein, pro-IL-1β, pro-IL-18 and pro-caspase-1), followed by Signal 2 or activation (expression of active...

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Bibliographic Details
Main Authors:	Abas, Razif, Wozniak, Marcin, Herbert, Karl
Format:	Article
Published:	Universiti Putra Malaysia 2019
Online Access:	http://psasir.upm.edu.my/id/eprint/99040/

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