An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge
Among the three subtypes of neurofibromatosis are type 1 and 2 neurofibromatosis and schwannomatosis, von Recklinghausen disease also known as type 1 neurofibromatosis has an autosomal dominant inheritance. It is the commonest form as and presents with numerous café-au-lait macules and neurofibromas...
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/98122/ http://psasir.upm.edu.my/id/eprint/98122/1/2022011912330354_MJMHS_1075.pdf |
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| author | Low, Qin Jian Lim, Tzyy Huei Lee, Ri An Cheo, See Wee Mohd Nasir, Noor ‘Ain Bakrin, Ikmal Hisyam Yap, Evelyn Wen Yee |
| author_facet | Low, Qin Jian Lim, Tzyy Huei Lee, Ri An Cheo, See Wee Mohd Nasir, Noor ‘Ain Bakrin, Ikmal Hisyam Yap, Evelyn Wen Yee |
| author_sort | Low, Qin Jian |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Among the three subtypes of neurofibromatosis are type 1 and 2 neurofibromatosis and schwannomatosis, von Recklinghausen disease also known as type 1 neurofibromatosis has an autosomal dominant inheritance. It is the commonest form as and presents with numerous café-au-lait macules and neurofibromas. Giant congenital melanocytic nevus (CGMN) on the other hand is characterized by a melanocytic proliferation that present at birth. CGMN develops due to a defective embryonic pigment cell (melanocyte) precursors development and are often present at birth. Giant congenital melanocytic nevus (CGMN) and type 1 neurofibromatosis may occur together rarely. Clinicians should be aware of the rare presentation of both CGMN and type 1 neurofibromatosis in a patient. |
| first_indexed | 2025-11-15T13:22:31Z |
| format | Article |
| id | upm-98122 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:22:31Z |
| publishDate | 2022 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-981222022-08-11T04:06:08Z http://psasir.upm.edu.my/id/eprint/98122/ An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge Low, Qin Jian Lim, Tzyy Huei Lee, Ri An Cheo, See Wee Mohd Nasir, Noor ‘Ain Bakrin, Ikmal Hisyam Yap, Evelyn Wen Yee Among the three subtypes of neurofibromatosis are type 1 and 2 neurofibromatosis and schwannomatosis, von Recklinghausen disease also known as type 1 neurofibromatosis has an autosomal dominant inheritance. It is the commonest form as and presents with numerous café-au-lait macules and neurofibromas. Giant congenital melanocytic nevus (CGMN) on the other hand is characterized by a melanocytic proliferation that present at birth. CGMN develops due to a defective embryonic pigment cell (melanocyte) precursors development and are often present at birth. Giant congenital melanocytic nevus (CGMN) and type 1 neurofibromatosis may occur together rarely. Clinicians should be aware of the rare presentation of both CGMN and type 1 neurofibromatosis in a patient. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2022-01 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/98122/1/2022011912330354_MJMHS_1075.pdf Low, Qin Jian and Lim, Tzyy Huei and Lee, Ri An and Cheo, See Wee and Mohd Nasir, Noor ‘Ain and Bakrin, Ikmal Hisyam and Yap, Evelyn Wen Yee (2022) An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge. Malaysian Journal of Medicine and Health Sciences, 18 (1). pp. 372-374. ISSN 2636-9346 https://medic.upm.edu.my/upload/dokumen/2022011912330354_MJMHS_1075.pdf |
| spellingShingle | Low, Qin Jian Lim, Tzyy Huei Lee, Ri An Cheo, See Wee Mohd Nasir, Noor ‘Ain Bakrin, Ikmal Hisyam Yap, Evelyn Wen Yee An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge |
| title | An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge |
| title_full | An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge |
| title_fullStr | An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge |
| title_full_unstemmed | An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge |
| title_short | An unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge |
| title_sort | unusual presentation of neurotized congenital giant melanocytic nevus and type 1 neurofibromatosis: a diagnostic challenge |
| url | http://psasir.upm.edu.my/id/eprint/98122/ http://psasir.upm.edu.my/id/eprint/98122/ http://psasir.upm.edu.my/id/eprint/98122/1/2022011912330354_MJMHS_1075.pdf |