Effect of ruxolitinib supplementation in enhancing neurogenesis via gliogenesis suppression in foetal mouse brain development

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Effect of ruxolitinib supplementation in enhancing neurogenesis via gliogenesis suppression in foetal mouse brain development

JAK-STAT pathway is important in regulating gliogenesis in the brain. Dysregulation of this pathway leads to abnormality in brain development as seen in Down syndrome individuals’ predominantly low initial neuron-glia ratio in early infancy. Thus, suppression of JAK-STAT pathway would be advantageou...

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Bibliographic Details
Main Author:	Hamzah, Hamizun
Format:	Thesis
Language:	English
Published:	2019
Subjects:	Neuroglia - physiology Janus Kinases
Online Access:	http://psasir.upm.edu.my/id/eprint/98051/ http://psasir.upm.edu.my/id/eprint/98051/1/FPSK%28m%29%202020%2045%20UPMIR.pdf

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