Abrogation of oncogenic k-ras function by andrographolide derivatives via in silico, in vitro, and in vivo approaches

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Abrogation of oncogenic k-ras function by andrographolide derivatives via in silico, in vitro, and in vivo approaches

The rat sarcoma (Ras) proteins are small guanosine triphosphatases (GTPases) that act as molecular switches in major signalling pathways involved in cell proliferation, differentiation, and survival, such as mitogenactivated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K) cascades...

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Bibliographic Details
Main Author:	Quah, Shun Ying
Format:	Thesis
Language:	English
Published:	2021
Subjects:	Neoplasms - therapy Genes, ras
Online Access:	http://psasir.upm.edu.my/id/eprint/97712/ http://psasir.upm.edu.my/id/eprint/97712/1/FPSK%28p%29%202021%2015%20-%20IR.1.pdf

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