Hepatitis B virus-like particle: targeted delivery of plasmid expressing short hairpin RNA for silencing the Bcl-2 gene in cervical cancer cells

QR Code

Hepatitis B virus-like particle: targeted delivery of plasmid expressing short hairpin RNA for silencing the Bcl-2 gene in cervical cancer cells

Gene therapy research has advanced to clinical trials, but it is hampered by unstable nucleic acids packaged inside carriers and there is a lack of specificity towards targeted sites in the body. This study aims to address gene therapy limitations by encapsidating a plasmid synthesizing a short hair...

Full description

Bibliographic Details
Main Authors:	Akwiditya, Made Angga, Yong, Chean Yeah, Yusof, Mohd Termizi, Abdul Razak, Mariatulqabtiah, Ho, Kok Lian, Tan, Wen Siang
Format:	Article
Language:	English
Published:	Multidisciplinary Digital Publishing Institute 2021
Online Access:	http://psasir.upm.edu.my/id/eprint/97514/ http://psasir.upm.edu.my/id/eprint/97514/1/ABSTRACT.pdf

Similar Items

Targeted delivery of short hairpin RNA expressing plasmid using hepatitis B virus-like particle for bcl-2 gene silencing in cervical cancer cells
by: Akwiditya, Made Angga
Published: (2021)

Shielding of hepatitis B virus-like nanoparticle with poly(2-ethyl-2-oxazoline)
by: Fam, See Yee, et al.
Published: (2019)

Chimeric virus-like particles of prawn nodavirus displaying hepatitis B virus immunodominant region: biophysical properties and cytokine response
by: Ninyio, Nathaniel Nyakaat, et al.
Published: (2021)

In-vitro investigations into endocytosis and silencing of siRNA-liposomes
by: ALSHEHRI, ABDULLAH ALI D
Published: (2017)

Macrobrachium rosenbergii de Man nodavirus capsid displaying Influenza A and Hepatitis B virus immunodominant regions induce humoral and cellular immune responses in mice
by: Yong, Chean Yeah
Published: (2015)

Immunological analysis of the Hepatitis B virus “a” determinant displayed on chimeric virus-like particles of Macrobrachium rosenbergii nodavirus capsid protein produced in Sf9 cells
by: Ninyio, Nathaniel Nyakaat, et al.
Published: (2020)

Performance of engineering plant virus resistance: miRNA gene silencing
by: Mohamed, Elizah, et al.
Published: (2022)

Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
by: Alshehri, Abdullah Ali, et al.
Published: (2018)

Single-step purification of recombinant hepatitis B core antigen Y132A dimer from clarified Escherichia coli feedstock using a packed bed anion exchange chromatography
by: Lim, Swee Lu, et al.
Published: (2018)

Single-step purification of recombinant hepatitis B core antigen Y132A dimer from clarified Escherichia coli feedstock using a packed bed anion exchange chromatography
by: lim, Swee Lu, et al.
Published: (2018)

Exosomal-microRNA transcriptome profiling of parental and CSC-like MDA-MB-231 cells in response to cisplatin treatment
by: Koh, May Zie, et al.
Published: (2022)

Virus-like particles of Macrobrachium rosenbergii nodavirus: particle size and capsid protein assembly domain
by: Ganesan, Hagilaa, et al.
Published: (2022)

A miniaturized hairpin resonator for the high selectivity of WLAN bandwidth
by: Azam, S. M. Kayser, et al.
Published: (2019)

Silence and silencing: the case of trafficked women
by: Haezreena Begum Abdul Hamid,
Published: (2019)

Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency
by: Capel, Victoria, et al.
Published: (2016)

(E)-Vinylphosphonates: nuclease-stable phosphate mimics for effective single-stranded RNA gene silencing
by: Al-Kadhimi, Mustafa M.
Published: (2020)

Experimental investigation of oil spray cooling in electrical machines with hairpin windings
by: Liu, Chuan
Published: (2020)

Design multilayer bandpass filter using hairpin resonator for digital broadcasting
by: Abdullah, Qazwan
Published: (2015)

Cartographies of silence: mapping concepts of silence and their contexts
by: Brown, Melissa Shani
Published: (2013)

Selective partition of plasmid DNA and RNA in aqueous two-phase systems by the addition of neutral salt.
by: Luechau, Frank, et al.
Published: (2009)

Virus-like particles of macrobrachium rosenbergii nodavirus capsid as a carrier for immunogenic components
by: Tan, Wen Siang, et al.
Published: (2014)

A compact bandpass filter using microstrip hairpin resonator for WLAN applications
by: Azam, S. M. Kayser, et al.
Published: (2018)

Targeted delivery of cell penetrating peptide virus-like nanoparticles to skin cancer cells
by: Gan, Bee Koon, et al.
Published: (2018)

Silencing the Ulama
by: Hussain, Mohd. Yusof
Published: (2012)

Redressing the Silence
by: Carpenter, Paul
Published: (2013)

The Power of Silence
by: Chrulew, Matthew
Published: (2014)

Small interfering RNA silencing of interleukin-6 in mesenchymal stromal cells inhibits multiple myeloma cell growth
by: Teoh, Hoon Koon, et al.
Published: (2016)

RNA interference silencing of interleukin-6 in mesenchymal stromal cells and antitumour efficacy against multiple myeloma cells
by: Teoh, Hoon Koon
Published: (2015)

X-band miniaturized wideband bandpass filter utilizing multilayered microstrip hairpin resonator
by: Adam, Helmi, et al.
Published: (2009)

A polyamidoamne dendrimer functionalized graphene oxide for DOX and MMP-9 shRNA plasmid co-delivery
by: Gu, Y., et al.
Published: (2017)

Effect of shRNA mediated silencing of YB-1 protein on the expression of matrix collagenases in malignant melanoma cell in vitro
by: Ibrahim, Wisam Nabeel, et al.
Published: (2018)

Prospective therapeutic strategies for cervical cancer
by: Mhd Zain, Nor Aini Lubis, et al.
Published: (2019)

Estimation of oil spray cooling heat transfer coefficients on hairpin windings with reduced-parameter models
by: Liu, Chuan, et al.
Published: (2020)

Multilayer hairpin bandpass filter for digital broadcasting / Robi'atun Adayiah Awang … [et al.]
by: Awang, Robi'atun Adayiah, et al.
Published: (2011)

Compact microwave hairpin line band pass filter using folded quarter-wave resonator
by: Dahlan, Samsul Haimi
Published: (2005)

Compact microwave hairpin line band pass filter using folded quarter-wave resonator
by: Dahlan, Samsul Haimi
Published: (2005)

Two-step process for initial capture of plasmid DNA and partial removal of RNA using aqueous two-phase systems.
by: Luechau, Frank, et al.
Published: (2010)

Negative chromatography of hepatitis B virus-like particles: comparative study of different adsorbent designs
by: Lee, Micky Fu Xiang, et al.
Published: (2016)

A hepatitis C virus cis-acting replication element forms a long-range RNA-RNA interaction with upstream RNA sequences in NS5B
by: Diviney, Sinead, et al.
Published: (2008)

Tracking the virus-like particles of Macrobrachium rosenbergii nodavirus in insect cells
by: Hanapi, Ummi Fairuz, et al.
Published: (2017)