Effects of transfusion and splenectomy on globin chain expression in NTDT HbE/β-thalassaemia

QR Code

Effects of transfusion and splenectomy on globin chain expression in NTDT HbE/β-thalassaemia

Introduction: Majority of HbE/β-thalassaemia patients resembles the phenotype of non-transfusion dependent thalassaemia (NTDT). Current management strategies are highly diverse, and the objective of this study is to examine the effects of different treatments on multiple parameters in NTDT HbE/β-tha...

Full description

Bibliographic Details
Main Authors:	Lim, Wai Feng, George, Elizabeth, Sathar, Jameela, Lai, Kuan Teh, Lai, Mei I.
Format:	Article
Language:	English
Published:	Universiti Putra Malaysia 2021
Online Access:	http://psasir.upm.edu.my/id/eprint/97018/ http://psasir.upm.edu.my/id/eprint/97018/1/2021120708172907_MJMHS_0777.pdf

Similar Items

HbE β-Thalassaemia in Malaysia: revisited
by: George, Elizabeth
Published: (2013)

Concurrent inheritance of deletional a-thalassaemia in Malays with HbE trait
by: Teh, Lai Kuan, et al.
Published: (2009)

HbA2 levels in β-thalassaemia carriers with the Filipino β0-deletion: are the levels higher than what is found with non-deletional forms of β0-thalassaemia?
by: George, Elizabeth, et al.
Published: (2013)

Association of Alpha Haemoglobin Stabilizing Protein in HbE/ Beta-Thalassaemia Patients in Malaysia
by: Lim, Wai Feng
Published: (2011)

The HbA2 levels in normal, B-thalassaemia and haemoglobin E heterozygotes and haemoglobin E (HbE) level in HbE heterozygotes by capillary electrophoresis system
by: Hafiza A,, et al.
Published: (2011)

Putative role of Bach1 gene in HbE/beta-thalassaemia patients
by: Lee, Tze Yan
Published: (2013)

Correlation of BACH1 and hemoglobin E/Beta-thalassemia globin expression
by: Tze, Yan Lee, et al.
Published: (2016)

Haplotype analysis of β-Thalassaemia major and carriers with Filipino β°-deletion in Sabah, Malaysia
by: Teh, Lai Kuan, et al.
Published: (2018)

Case series of homozygous and compound heterozygosity of Hb Malay, the diagnostic features and transfusion requirements
by: Amran, Hanizah Salwa, et al.
Published: (2017)

Hb lepore/β0-thalassaemia with α+-thalassaemia interactions, a potential diagnostic pitfall
by: Hafiza, Alauddin, et al.
Published: (2015)

An assessment of three noncommercial DNA extraction methods from dried blood spots for beta-thalassaemia mutation identification.
by: Kartipan, S. N., et al.
Published: (2011)

Interaction of Hb South Florida (codon 1; GTG→ATG) and HbE, with β-thalassemia (IVS1-1; G→A): expression of different clinical phenotypes
by: Tan, Mary Anne Jin Ai, et al.
Published: (2009)

Serum soluble transferrin receptor concentration as a biomarker of erythropoietic activity: surrogate marker of adequate transfusion in adult Beta-thalassaemia intermedia patients
by: Chellappah Thambiah, Subashini, et al.
Published: (2013)

HbE dan diabetis melitus lapuran akhir projek jangka
by: Mazlan, Musalmah, et al.
Published: (2003)

Molecular characterisation of β-globin gene mutations in Penang and Kedah, Malaysia
by: Kho, Siew Leng, et al.
Published: (2014)

Transfusion transmitted malaria in a thalassaemia major patient
by: Anuar, Nur Aliaa, et al.
Published: (2020)

Differential gene expression Analyses in HBE/BETA thalassaemia patients and their relationship to disease severity
by: Alsaleh, Heba A. A.
Published: (2022)

A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC)
by: George, Elizabeth, et al.
Published: (2009)

Molecular characterisation of beta thalassaemia in patients from Sabah, Malaysia
by: Teh, Lai Kuan
Published: (2014)

Craniofacial And Dental Arches Characteristics In Transfusion Dependent Thalassaemia Patients
by: Fattah Toman, Heba Ahmed Abdel
Published: (2009)

Molecular basis of transfusion dependent beta-thalassemia major patients in Sabah
by: Teh, Lai Kuan, et al.
Published: (2014)

Expression Level of Pro-Apoptotic Genes Determine Disease Severity of HbE/Beta thalassemia
by: Hassan, Rosline
Published: (2019)

Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients
by: Mohammed Ibraheem, Shahad, et al.
Published: (2022)

Identification of α°-thalassaemia (–SEA) using an enzyme-linked immunosorbent assay (ELISA) for embryonic zeta-globin chain detection – a preliminary study
by: Tan, Mary Anne Jin Ai, et al.
Published: (2006)

Economic Analysis Of Transfusion Dependent Thalassaemia (Tdt) And Deferasirox Fct Efficiency In Malaysia
by: Wong, Jacqueline Hui Yi
Published: (2020)

Rapid detection of α-thalassaemia variants using droplet digital PCR
by: Lee, Tze Yan, et al.
Published: (2016)

The novel role of the B-cell lymphoma/leukemia 11A (BCL11A) gene in β-thalassaemia treatment
by: Lai, Mei I, et al.
Published: (2023)

Development of reverse dot blot hybridisation strip assays to identify common beta-thalassaemia alleles in Malays and Chinese in Malaysia
by: Teh, Lai Kuan
Published: (2010)

Children with transfusion dependent thalassaemia : the study of psychological distress and coping strategies among caretakers
by: Ghani, Mohd. Sufian Ardi Abd.
Published: (2016)

Screening of thalassaemia carriers and its limitations
by: George, Elizabeth
Published: (2014)

Determination of alpha hemoglobin stabilizing protein (AHSP) gene expression and oxidative stress parameters in HbE/beta-Thalassemia
by: Yaacob, Nur Suraya Che
Published: (2021)

Screening for intermediate and severe forms of thalassaemia in discarded red blood cells: optimization and feasibility
by: George, Elizabeth, et al.
Published: (2011)

Alpha thalassaemia due to non-deletional mutations on the -3.7 alpha globin fusion gene: Laboratory diagnosis and clinical importance
by: Chow, A., et al.
Published: (2013)

Clinico-haematological profiling of transfusion dependent and non transfucion dependent beta thalassaemia syndrome in Kedah
by: Azizi, Fahmaa
Published: (2020)

Reviewing the compounding risks for tuberculosis drug-induced liver injury in a patient with transfusion dependent thalassaemia
by: Rofii, Nursafinas, et al.
Published: (2023)

Comparison of macular thickness, retinal nerve fiber layer thickness and optic nerve head parameters in HbE/Beta thalassemia and control
by: Dezhao, Sai
Published: (2016)

Reduction of Tear-Drop poikilocytes in a case of myelofibrosis following splenectomy
by: Chooi-Fun Leong,, et al.
Published: (2006)

Non-deletional alpha thalassaemia: a review of emerging therapy
by: Khairil Wahidin, Nurfhaezah, et al.
Published: (2021)

Detection of β-Globin Gene Polymorphisms Using Real Time PCR-High Resolution Melting Method in Selected Iranian β-Thalassemia Patients
by: Marashi, Syed Jalal
Published: (2011)

Analysis of a1 and a2 globin genes among patients with hemoglobin Adana in Malaysia
by: Lee, T. Y., et al.
Published: (2016)