Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network
Background: The application of deep learning models to electroencephalogram (EEG) signal classification has recently become a popular research topic. Several deep learning models have been proposed to classify EEG signals in patients with various neurological diseases. However, no effective deep lea...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
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Elsevier
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/96396/ |
| _version_ | 1848862355481427968 |
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| author | Wen, Dong Cheng, Zihao Li, Jingjing Zheng, Xinxiang Yao, Wang Dong, Xianling Saripan, M. Iqbal Li, Xiaoli Yin, Shimin Zhou, Yanhong |
| author_facet | Wen, Dong Cheng, Zihao Li, Jingjing Zheng, Xinxiang Yao, Wang Dong, Xianling Saripan, M. Iqbal Li, Xiaoli Yin, Shimin Zhou, Yanhong |
| author_sort | Wen, Dong |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: The application of deep learning models to electroencephalogram (EEG) signal classification has recently become a popular research topic. Several deep learning models have been proposed to classify EEG signals in patients with various neurological diseases. However, no effective deep learning model for event-related potential (ERP) signal classification is yet available for amnestic mild cognitive impairment (aMCI) with type 2 diabetes mellitus (T2DM). Method: This study proposed a single-scale multi-input convolutional neural network (SSMICNN) method to classify ERP signals between aMCI patients with T2DM and the control group. Firstly, the 18-electrode ERP signal on alpha, beta, and theta frequency bands was extracted by using the fast Fourier transform, and then the mean, sum of squares, and absolute value feature of each frequency band were calculated. Finally, these three features are converted into multispectral images respectively and used as the input of the SSMICNN network to realize the classification task.
Results: The results show that the SSMICNN can fuse MSI formed by different features, SSMICNN enriches the feature quantity of the neural network input layer and has excellent robustness, and the errors of SSMICNN can be simultaneously transmitted to the three convolution channels in the back-propagation phase. Comparison with Existing Method(s): SSMICNN could more effectively identify ERP signals from aMCI with T2DM from the control group compared to existing classification methods, including convolution neural network, support vector machine, and logistic regression. Conclusions: The combination of SSMICNN and MSI can be used as an effective biological marker to distinguish aMCI patients with T2DM from the control group. |
| first_indexed | 2025-11-15T13:15:42Z |
| format | Article |
| id | upm-96396 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:15:42Z |
| publishDate | 2021 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-963962023-01-30T06:56:49Z http://psasir.upm.edu.my/id/eprint/96396/ Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network Wen, Dong Cheng, Zihao Li, Jingjing Zheng, Xinxiang Yao, Wang Dong, Xianling Saripan, M. Iqbal Li, Xiaoli Yin, Shimin Zhou, Yanhong Background: The application of deep learning models to electroencephalogram (EEG) signal classification has recently become a popular research topic. Several deep learning models have been proposed to classify EEG signals in patients with various neurological diseases. However, no effective deep learning model for event-related potential (ERP) signal classification is yet available for amnestic mild cognitive impairment (aMCI) with type 2 diabetes mellitus (T2DM). Method: This study proposed a single-scale multi-input convolutional neural network (SSMICNN) method to classify ERP signals between aMCI patients with T2DM and the control group. Firstly, the 18-electrode ERP signal on alpha, beta, and theta frequency bands was extracted by using the fast Fourier transform, and then the mean, sum of squares, and absolute value feature of each frequency band were calculated. Finally, these three features are converted into multispectral images respectively and used as the input of the SSMICNN network to realize the classification task. Results: The results show that the SSMICNN can fuse MSI formed by different features, SSMICNN enriches the feature quantity of the neural network input layer and has excellent robustness, and the errors of SSMICNN can be simultaneously transmitted to the three convolution channels in the back-propagation phase. Comparison with Existing Method(s): SSMICNN could more effectively identify ERP signals from aMCI with T2DM from the control group compared to existing classification methods, including convolution neural network, support vector machine, and logistic regression. Conclusions: The combination of SSMICNN and MSI can be used as an effective biological marker to distinguish aMCI patients with T2DM from the control group. Elsevier 2021 Article PeerReviewed Wen, Dong and Cheng, Zihao and Li, Jingjing and Zheng, Xinxiang and Yao, Wang and Dong, Xianling and Saripan, M. Iqbal and Li, Xiaoli and Yin, Shimin and Zhou, Yanhong (2021) Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network. Journal of Neuroscience Methods, 363. art. no. 109353. pp. 1-12. ISSN 0165-0270 https://www.sciencedirect.com/science/article/pii/S0165027021002880?via%3Dihub 10.1016/j.jneumeth.2021.109353 |
| spellingShingle | Wen, Dong Cheng, Zihao Li, Jingjing Zheng, Xinxiang Yao, Wang Dong, Xianling Saripan, M. Iqbal Li, Xiaoli Yin, Shimin Zhou, Yanhong Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network |
| title | Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network |
| title_full | Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network |
| title_fullStr | Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network |
| title_full_unstemmed | Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network |
| title_short | Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network |
| title_sort | classification of erp signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network |
| url | http://psasir.upm.edu.my/id/eprint/96396/ http://psasir.upm.edu.my/id/eprint/96396/ http://psasir.upm.edu.my/id/eprint/96396/ |