Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts
The 70% ethanolic extracts from eight neglected fruits; Muntingia calabura, Leucaena leucocephala, Spondias dulcis, Syzygium jambos, Mangifera caesia, Ardisia elliptica, Cynometra cauliflora and Ficus auriculata were evaluated for their 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, α...
| Main Authors: | , , , , , |
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| Format: | Article |
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Springer
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/95928/ |
| _version_ | 1848862256098443264 |
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| author | Mohamed Yunus, Siti Norhamimah Abas, Faridah Jaafar, Ahmad Haniff Azizan, Awanis Zolkeflee, Nur Khaleeda Zulaikha Abd Ghafar, Siti Zulaikha |
| author_facet | Mohamed Yunus, Siti Norhamimah Abas, Faridah Jaafar, Ahmad Haniff Azizan, Awanis Zolkeflee, Nur Khaleeda Zulaikha Abd Ghafar, Siti Zulaikha |
| author_sort | Mohamed Yunus, Siti Norhamimah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The 70% ethanolic extracts from eight neglected fruits; Muntingia calabura, Leucaena leucocephala, Spondias dulcis, Syzygium jambos, Mangifera caesia, Ardisia elliptica, Cynometra cauliflora and Ficus auriculata were evaluated for their 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, α-glucosidase inhibitory activities as well as total phenolic content. The results of this study revealed that M. caesia fruit extract demonstrated the most potent radical scavenging activity. Among the fruits examined for α-glucosidase inhibitory activity, M. calabura and F. auriculata exhibited strong activity with no significant difference. The Pearson correlation indicated that the activities of M. caesia and F. auriculata contributed by phenolic compounds. A total of 65 metabolites were tentatively identified by using ultra-high-performance liquid chromatography tandem mass spectrometry (UHLPC-MS/MS). These findings suggested that the possible application of M. caesia and F. auriculata as a functional food with antioxidant and α-glucosidase inhibitory properties. |
| first_indexed | 2025-11-15T13:14:08Z |
| format | Article |
| id | upm-95928 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:14:08Z |
| publishDate | 2021 |
| publisher | Springer |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-959282023-03-21T04:58:32Z http://psasir.upm.edu.my/id/eprint/95928/ Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts Mohamed Yunus, Siti Norhamimah Abas, Faridah Jaafar, Ahmad Haniff Azizan, Awanis Zolkeflee, Nur Khaleeda Zulaikha Abd Ghafar, Siti Zulaikha The 70% ethanolic extracts from eight neglected fruits; Muntingia calabura, Leucaena leucocephala, Spondias dulcis, Syzygium jambos, Mangifera caesia, Ardisia elliptica, Cynometra cauliflora and Ficus auriculata were evaluated for their 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, α-glucosidase inhibitory activities as well as total phenolic content. The results of this study revealed that M. caesia fruit extract demonstrated the most potent radical scavenging activity. Among the fruits examined for α-glucosidase inhibitory activity, M. calabura and F. auriculata exhibited strong activity with no significant difference. The Pearson correlation indicated that the activities of M. caesia and F. auriculata contributed by phenolic compounds. A total of 65 metabolites were tentatively identified by using ultra-high-performance liquid chromatography tandem mass spectrometry (UHLPC-MS/MS). These findings suggested that the possible application of M. caesia and F. auriculata as a functional food with antioxidant and α-glucosidase inhibitory properties. Springer 2021 Article PeerReviewed Mohamed Yunus, Siti Norhamimah and Abas, Faridah and Jaafar, Ahmad Haniff and Azizan, Awanis and Zolkeflee, Nur Khaleeda Zulaikha and Abd Ghafar, Siti Zulaikha (2021) Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts. Food Science and Biotechnology, 30 (2). 195 - 208. ISSN 1226-7708; ESSN: 2092-6456 https://link.springer.com/article/10.1007/s10068-020-00856-x 10.1007/s10068-020-00856-x |
| spellingShingle | Mohamed Yunus, Siti Norhamimah Abas, Faridah Jaafar, Ahmad Haniff Azizan, Awanis Zolkeflee, Nur Khaleeda Zulaikha Abd Ghafar, Siti Zulaikha Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts |
| title | Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts |
| title_full | Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts |
| title_fullStr | Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts |
| title_full_unstemmed | Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts |
| title_short | Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts |
| title_sort | antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and uhplc-ms/ms profile of the active extracts |
| url | http://psasir.upm.edu.my/id/eprint/95928/ http://psasir.upm.edu.my/id/eprint/95928/ http://psasir.upm.edu.my/id/eprint/95928/ |