Animal coronavirus diseases: parallels with COVID-19 in humans
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus in humans, has expanded globally over the past year. COVID-19 remains an important subject of intensive research owing to its huge impact on economic and public health glo...
| Main Authors: | , , , , , , |
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| Format: | Article |
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Multidisciplinary Digital Publishing Institute
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/95855/ |
| _version_ | 1848862236219539456 |
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| author | Lin, Chao Nan Kuan, Rong Chan Eng, Eong Ooi Ming, Tang Chiou Hoang, Minh Hsueh, Po Ren Ooi, Peck Toung |
| author_facet | Lin, Chao Nan Kuan, Rong Chan Eng, Eong Ooi Ming, Tang Chiou Hoang, Minh Hsueh, Po Ren Ooi, Peck Toung |
| author_sort | Lin, Chao Nan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus in humans, has expanded globally over the past year. COVID-19 remains an important subject of intensive research owing to its huge impact on economic and public health globally. Based on historical archives, the first coronavirus-related disease recorded was possibly animal-related, a case of feline infectious peritonitis described as early as 1912. Despite over a century of documented coronaviruses in animals, the global animal industry still suffers from outbreaks. Knowledge and experience handling animal coronaviruses provide a valuable tool to complement our understanding of the ongoing COVID-19 pandemic. In this review, we present an overview of coronaviruses, clinical signs, COVID-19 in animals, genome organization and recombination, immunopathogenesis, transmission, viral shedding, diagnosis, treatment, and prevention. By drawing parallels between COVID-19 in animals and humans, we provide perspectives on the pathophysiological mechanisms by which coronaviruses cause diseases in both animals and humans, providing a critical basis for the development of effective vaccines and therapeutics against these deadly viruses. |
| first_indexed | 2025-11-15T13:13:49Z |
| format | Article |
| id | upm-95855 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:13:49Z |
| publishDate | 2021 |
| publisher | Multidisciplinary Digital Publishing Institute |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-958552023-03-28T07:56:48Z http://psasir.upm.edu.my/id/eprint/95855/ Animal coronavirus diseases: parallels with COVID-19 in humans Lin, Chao Nan Kuan, Rong Chan Eng, Eong Ooi Ming, Tang Chiou Hoang, Minh Hsueh, Po Ren Ooi, Peck Toung Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus in humans, has expanded globally over the past year. COVID-19 remains an important subject of intensive research owing to its huge impact on economic and public health globally. Based on historical archives, the first coronavirus-related disease recorded was possibly animal-related, a case of feline infectious peritonitis described as early as 1912. Despite over a century of documented coronaviruses in animals, the global animal industry still suffers from outbreaks. Knowledge and experience handling animal coronaviruses provide a valuable tool to complement our understanding of the ongoing COVID-19 pandemic. In this review, we present an overview of coronaviruses, clinical signs, COVID-19 in animals, genome organization and recombination, immunopathogenesis, transmission, viral shedding, diagnosis, treatment, and prevention. By drawing parallels between COVID-19 in animals and humans, we provide perspectives on the pathophysiological mechanisms by which coronaviruses cause diseases in both animals and humans, providing a critical basis for the development of effective vaccines and therapeutics against these deadly viruses. Multidisciplinary Digital Publishing Institute 2021 Article PeerReviewed Lin, Chao Nan and Kuan, Rong Chan and Eng, Eong Ooi and Ming, Tang Chiou and Hoang, Minh and Hsueh, Po Ren and Ooi, Peck Toung (2021) Animal coronavirus diseases: parallels with COVID-19 in humans. Viruses-Basel, 13 (8). art. no. 1507. pp. 1-16. ISSN 1999-4915 https://www.mdpi.com/1999-4915/13/8/1507 10.3390/v13081507 |
| spellingShingle | Lin, Chao Nan Kuan, Rong Chan Eng, Eong Ooi Ming, Tang Chiou Hoang, Minh Hsueh, Po Ren Ooi, Peck Toung Animal coronavirus diseases: parallels with COVID-19 in humans |
| title | Animal coronavirus diseases: parallels with COVID-19 in humans |
| title_full | Animal coronavirus diseases: parallels with COVID-19 in humans |
| title_fullStr | Animal coronavirus diseases: parallels with COVID-19 in humans |
| title_full_unstemmed | Animal coronavirus diseases: parallels with COVID-19 in humans |
| title_short | Animal coronavirus diseases: parallels with COVID-19 in humans |
| title_sort | animal coronavirus diseases: parallels with covid-19 in humans |
| url | http://psasir.upm.edu.my/id/eprint/95855/ http://psasir.upm.edu.my/id/eprint/95855/ http://psasir.upm.edu.my/id/eprint/95855/ |