The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19

Objective: Examination of the diagnostic covid-19 gold standard with real time reverse polymerase chain reaction (RT-PCR) is still limited, so that the initial hematological examination (leukocytes, lymphocytes, neutrophils, platelets, hemoglobin, and neutrophil lymphocyte ratio (NLR) plays an impor...

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Main Authors: Winarno, Didik Dwi, Tualeka, Abdul Rohim, Widajati, Noeroel, Jalaludin, Juliana, Huda, Nuh, Raden Khairiyatul Afiyah, Rahman, Firman Suryadi
Format: Article
Language:English
Published: Institute of Medico-Legal Publications 2021
Online Access:http://psasir.upm.edu.my/id/eprint/95397/
http://psasir.upm.edu.my/id/eprint/95397/1/The%20effect%20of%20nitric%20oxide%20supplement%20intake%20on%20the%20value%20of%20hematological%20examination%20of%20health%20workers%20exposed%20to%20Covid-19.pdf
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author Winarno, Didik Dwi
Tualeka, Abdul Rohim
Widajati, Noeroel
Jalaludin, Juliana
Huda, Nuh
Raden Khairiyatul Afiyah
Rahman, Firman Suryadi
author_facet Winarno, Didik Dwi
Tualeka, Abdul Rohim
Widajati, Noeroel
Jalaludin, Juliana
Huda, Nuh
Raden Khairiyatul Afiyah
Rahman, Firman Suryadi
author_sort Winarno, Didik Dwi
building UPM Institutional Repository
collection Online Access
description Objective: Examination of the diagnostic covid-19 gold standard with real time reverse polymerase chain reaction (RT-PCR) is still limited, so that the initial hematological examination (leukocytes, lymphocytes, neutrophils, platelets, hemoglobin, and neutrophil lymphocyte ratio (NLR) plays an important role in monitoring the course of covid-19 disease Macrophages release nitric oxide (NO) to kill parasites NO inhibits migration and adhesion of leucocytes to the endothelium. Metode: The research design used preexperimental with one group pre-post test, the total sample was 80 health workers who were exposed to Covid-19, the independent variable was the provision of NO and the dependent variable was the result of a hematological examination (leukocytes, lymposites, platelets, neutrophils, hemoglobin and NLR). The intervention was given NO 500 mg mixed with warm water 250 cc, given 3 times a day for 5 days, data analysis used the T-test with a significance value of a<0.05. Results: There is a difference in the results of the pre and post-test hematology giving NO to the results of the examination of leucocytes a=0.001, lymphocytes a=0.000, platelets a=0.000, neutrophils a=0.000, hemoglobin a=0.031, and NLR a=0.000. Conclusion: Giving NO to health workers exposed to Covid-19 can improve the hematology and immune systems to fight the corona virus.
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spelling upm-953972023-01-05T08:57:23Z http://psasir.upm.edu.my/id/eprint/95397/ The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19 Winarno, Didik Dwi Tualeka, Abdul Rohim Widajati, Noeroel Jalaludin, Juliana Huda, Nuh Raden Khairiyatul Afiyah Rahman, Firman Suryadi Objective: Examination of the diagnostic covid-19 gold standard with real time reverse polymerase chain reaction (RT-PCR) is still limited, so that the initial hematological examination (leukocytes, lymphocytes, neutrophils, platelets, hemoglobin, and neutrophil lymphocyte ratio (NLR) plays an important role in monitoring the course of covid-19 disease Macrophages release nitric oxide (NO) to kill parasites NO inhibits migration and adhesion of leucocytes to the endothelium. Metode: The research design used preexperimental with one group pre-post test, the total sample was 80 health workers who were exposed to Covid-19, the independent variable was the provision of NO and the dependent variable was the result of a hematological examination (leukocytes, lymposites, platelets, neutrophils, hemoglobin and NLR). The intervention was given NO 500 mg mixed with warm water 250 cc, given 3 times a day for 5 days, data analysis used the T-test with a significance value of a<0.05. Results: There is a difference in the results of the pre and post-test hematology giving NO to the results of the examination of leucocytes a=0.001, lymphocytes a=0.000, platelets a=0.000, neutrophils a=0.000, hemoglobin a=0.031, and NLR a=0.000. Conclusion: Giving NO to health workers exposed to Covid-19 can improve the hematology and immune systems to fight the corona virus. Institute of Medico-Legal Publications 2021-03-24 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/95397/1/The%20effect%20of%20nitric%20oxide%20supplement%20intake%20on%20the%20value%20of%20hematological%20examination%20of%20health%20workers%20exposed%20to%20Covid-19.pdf Winarno, Didik Dwi and Tualeka, Abdul Rohim and Widajati, Noeroel and Jalaludin, Juliana and Huda, Nuh and Raden Khairiyatul Afiyah and Rahman, Firman Suryadi (2021) The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19. Indian Journal of Forensic Medicine and Toxicology, 15 (2). 2245 - 2251. ISSN 0973-9122; ESSN: 0973-9130 https://medicopublication.com/index.php/ijfmt/article/view/14706 10.37506/ijfmt.v15i2.14706
spellingShingle Winarno, Didik Dwi
Tualeka, Abdul Rohim
Widajati, Noeroel
Jalaludin, Juliana
Huda, Nuh
Raden Khairiyatul Afiyah
Rahman, Firman Suryadi
The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19
title The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19
title_full The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19
title_fullStr The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19
title_full_unstemmed The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19
title_short The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to Covid-19
title_sort effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to covid-19
url http://psasir.upm.edu.my/id/eprint/95397/
http://psasir.upm.edu.my/id/eprint/95397/
http://psasir.upm.edu.my/id/eprint/95397/
http://psasir.upm.edu.my/id/eprint/95397/1/The%20effect%20of%20nitric%20oxide%20supplement%20intake%20on%20the%20value%20of%20hematological%20examination%20of%20health%20workers%20exposed%20to%20Covid-19.pdf