Synthesis of small molecules targeting paclitaxel-induced MyD88 expression in triple-negative breast cancer cell lines
Acquired paclitaxel (PTX) chemoresistance in triple-negative breast cancer (TNBC) can be inferred from the overexpression of toll-like receptor 4 (TLR4) and myeloid differentiation primary response 88 (MyD88) proteins and the activation of the TLR4/MyD88 cascading signalling pathway. Finding a new i...
| Main Authors: | Khor, Poh Yen, Stanslas, Johnson, Zhang, Tianshu, Li, Hongyuan, Wang, Xiaohui, Chan, Kok Meng, Lam, Kok Wai |
|---|---|
| Format: | Article |
| Published: |
Elsevier
2021
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/95274/ |
Similar Items
Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways
by: Ismail, Elysha Nur, et al.
Published: (2020)
by: Ismail, Elysha Nur, et al.
Published: (2020)
The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88
by: Puneet, P., et al.
Published: (2011)
by: Puneet, P., et al.
Published: (2011)
The association of ICAM-1 detected by immunohistochemical staining with triple negative and non-triple negative breast carcinoma
by: Chong, Choi Yen, et al.
Published: (2019)
by: Chong, Choi Yen, et al.
Published: (2019)
Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer
by: Dent, R., et al.
Published: (2013)
by: Dent, R., et al.
Published: (2013)
PEGylation of paclitaxel for inhaled chemotherapy
by: Luo, Tian
Published: (2016)
by: Luo, Tian
Published: (2016)
Potential role of targeted therapies in the treatment of triple-negative breast cancer
by: Jia, L., et al.
Published: (2016)
by: Jia, L., et al.
Published: (2016)
Wnt signaling in triple-negative breast cancer
by: Pohl, S., et al.
Published: (2017)
by: Pohl, S., et al.
Published: (2017)
Investigations of bioresponsive polymers in triple negative breast cancers
by: Monteiro, Patricia
Published: (2019)
by: Monteiro, Patricia
Published: (2019)
Triple negative breast cancer in Asia: An insider's view
by: Wang, C., et al.
Published: (2018)
by: Wang, C., et al.
Published: (2018)
The role of HOXA5 in triple-negative breast cancer (TNBC)
by: Mahmoud, Rinad
Published: (2021)
by: Mahmoud, Rinad
Published: (2021)
Integrative molecular and pathologic profiling of triple negative breast cancer
by: Alsaleem, Mansour
Published: (2021)
by: Alsaleem, Mansour
Published: (2021)
Recent advances in nanotheranostics for triple negative breast cancer treatment
by: Thakur, Vikram, et al.
Published: (2019)
by: Thakur, Vikram, et al.
Published: (2019)
Comparing neoadjuvant nab-paclitaxel vs paclitaxel both followed by anthracycline regimens in women with ERBB2/ HER2-negative breast cancer-the evaluating treatment with neoadjuvant abraxane (ETNA) trial a randomized phase 3 clinical trial
by: Gianni, L., et al.
Published: (2018)
by: Gianni, L., et al.
Published: (2018)
Targeted delivery of vitamin E TPGS based nanomedicine for treatment of triple negative breast cancer
by: Rajaletchumy, Veloo Kutty
Published: (2015)
by: Rajaletchumy, Veloo Kutty
Published: (2015)
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
by: Shah, S., et al.
Published: (2012)
by: Shah, S., et al.
Published: (2012)
The identification of targeting peptides and tumour associated antigens for the treatment and early detection of triple negative breast cancer
by: Wilde, Megan
Published: (2023)
by: Wilde, Megan
Published: (2023)
The role of sodium driven bicarbonate transporters in triple negative breast cancer metastasis
by: Carroll, Christopher
Published: (2020)
by: Carroll, Christopher
Published: (2020)
A clinicopathologic study on triple-negative breast cancer patients: HUSM experience
by: Saidin, Usman Sani
Published: (2011)
by: Saidin, Usman Sani
Published: (2011)
Genetic determinants of TAC chemotherapy response in triple negative breast cancer patients
by: Aziz, Ahmad Aizat Abdul
Published: (2018)
by: Aziz, Ahmad Aizat Abdul
Published: (2018)
In silico investigations and potential approaches of Tectona grandis via targeting MMP-9 for triple negative breast cancer
by: Permana, Sofy, et al.
Published: (2024)
by: Permana, Sofy, et al.
Published: (2024)
Peptide-based and small molecule PD-1 and PD-L1 pharmacological modulators in the treatment of cancer
by: Islam, Mohammad Kaisarul, et al.
Published: (2021)
by: Islam, Mohammad Kaisarul, et al.
Published: (2021)
Calpain system protein expression in basal-like and
triple-negative invasive breast cancer
by: Storr, Sarah J., et al.
Published: (2012)
by: Storr, Sarah J., et al.
Published: (2012)
Apoptosis and cell cycle mechanisms of ampelopsin E on triple negative breast cancer cells
by: Abd Rahman, Napsiah
Published: (2017)
by: Abd Rahman, Napsiah
Published: (2017)
Assessment of cytotoxicity potency of paclitaxel in combination with Clinacanthus Nutans extracts on human MDA-MB-231 breast cancer cells
by: Nur Hasnieza Mohd Rosli,, et al.
Published: (2018)
by: Nur Hasnieza Mohd Rosli,, et al.
Published: (2018)
The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells
by: Etti, Imaobong Christopher, et al.
Published: (2017)
by: Etti, Imaobong Christopher, et al.
Published: (2017)
Immunomodulatory potential of Clinacanthus nutans extracts in the co-culture of triple-negative breast cancer cells, MDA-MB-231, and THP-1 macrophages
by: Nordin, Fariza Juliana, et al.
Published: (2021)
by: Nordin, Fariza Juliana, et al.
Published: (2021)
Passerini multicomponent reaction: a versatile synthesis of nanomedicines for triple negative breast cancer treatment
by: Travanut, Alessandra
Published: (2021)
by: Travanut, Alessandra
Published: (2021)
Mediation of triple-negative breast cancer cell fate via cellular redox and Wnt signalling
by: Pohl, Sebastian Öther-Gee
Published: (2018)
by: Pohl, Sebastian Öther-Gee
Published: (2018)
Systematic review on the efficacy and safety of ixabepilone-based chemotherapy regimen in triple-negative breast cancer
by: Azizah, Maghfira Rahma, et al.
Published: (2024)
by: Azizah, Maghfira Rahma, et al.
Published: (2024)
Cytotoxic effects of paclitaxel-loaded hyaluronic acid nanoparticle on selected cancer cell lines
by: Chaudhry, Gul E Saba, et al.
Published: (2016)
by: Chaudhry, Gul E Saba, et al.
Published: (2016)
Evaluation of the co-delivery of diagnostic and therapeutic agents in polymeric micelles for triple negative breats cancer treatment
by: Nurul Issttifa Iyah, Aminuddin, et al.
Published: (2019)
by: Nurul Issttifa Iyah, Aminuddin, et al.
Published: (2019)
Ampelopsin E reduces the invasiveness of the triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu, et al.
Published: (2019)
by: Tieng, Francis Yew Fu, et al.
Published: (2019)
PARP inhibitor combinations with Olaparib for synergistic efficacy in Olaparib-resistant triple-negative breast cancer cells
by: Yusoh, Nur Aininie
Published: (2023)
by: Yusoh, Nur Aininie
Published: (2023)
Synergistic Anticancer Effects Achieved by Co-Delivery of TRAIL and Paclitaxel Using Cationic Polymeric Micelles
by: Lee, A., et al.
Published: (2011)
by: Lee, A., et al.
Published: (2011)
Synergistic effects of Gefitinib and Paclitaxel in breast cancer treatment using cockle shell-derived nanoparticle
by: Chemmalar, Sangaran
Published: (2023)
by: Chemmalar, Sangaran
Published: (2023)
Profiling of gene and exosomal microRNA as therapy targets and biomarkers of cisplatin resistance in triple negative breast cancer stem cell-like subpopulation
by: Koh, May Zie
Published: (2021)
by: Koh, May Zie
Published: (2021)
Examining the mechanism of action of small-molecule negative allosteric modulators of the human chemokine receptor CXCR2
by: Nesheva, Desislava
Published: (2022)
by: Nesheva, Desislava
Published: (2022)
High CD4+/CD8+ Intratumour Ratio is associated with favourable outcome in triple-negative Breast Cancer
by: Thian, Q.Z., et al.
Published: (2022)
by: Thian, Q.Z., et al.
Published: (2022)
Effects of ampelopsin E towards the invasiveness of triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu
Published: (2019)
by: Tieng, Francis Yew Fu
Published: (2019)
Therapeutic potential of albumin nanoparticles encapsulated visnagin in MDA-MB-468 triple-negative breast cancer cells
by: Alsrhani, Abdullah, et al.
Published: (2023)
by: Alsrhani, Abdullah, et al.
Published: (2023)
Similar Items
-
Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways
by: Ismail, Elysha Nur, et al.
Published: (2020) -
The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88
by: Puneet, P., et al.
Published: (2011) -
The association of ICAM-1 detected by immunohistochemical staining with triple negative and non-triple negative breast carcinoma
by: Chong, Choi Yen, et al.
Published: (2019) -
Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer
by: Dent, R., et al.
Published: (2013) -
PEGylation of paclitaxel for inhaled chemotherapy
by: Luo, Tian
Published: (2016)