Synthesis and optimization of mesoporous silica nanoparticles for ruthenium polypyridyl drug delivery
The ruthenium polypyridyl complex [Ru(dppz)2PIP]2+ (dppz: dipyridophenazine, PIP: (2-(phenyl)-imidazo[4,5-f ][1,10]phenanthroline), or Ru-PIP, is a potential anticancer drug that acts by inhibiting DNA replication. Due to the poor dissolution of Ru-PIP in aqueous media, a drug delivery agent would b...
| Main Authors: | Harun, Siti Norain, Ahmad, Haslina, Lim, Hong Ngee, Chia, Suet Lin, Gill, Martin R. |
|---|---|
| Format: | Article |
| Published: |
MDPI AG
2021
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/95261/ |
Similar Items
Synthesis, cytotoxicity and dna binding studies of ruthenium(ii) mixed-polypyridyl complexes
by: Harun, Siti Norain
Published: (2015)
by: Harun, Siti Norain
Published: (2015)
A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition
by: Gill, Martin R., et al.
Published: (2016)
by: Gill, Martin R., et al.
Published: (2016)
Nanosized mesoporous silicas for drug delivery
by: Li, Ka, et al.
Published: (2009)
by: Li, Ka, et al.
Published: (2009)
Ruthenium(II) Polypyridyl Complexes as FRET donors: structure- and sequence-selective DNA-binding and anticancer properties
by: Elgar, Christopher E., et al.
Published: (2023)
by: Elgar, Christopher E., et al.
Published: (2023)
Ruthenium(ii) Polypyridyl complexes as FRET donors: structure- and sequence-selective DNA binding and anti-cancer properties
by: E. Elgar, Christopher, et al.
Published: (2023)
by: E. Elgar, Christopher, et al.
Published: (2023)
Functionalized ionic-liquid templated mesoporous silica nanoparticles for anticancer drug delivery system
by: Zaharudin, Nurul Syahira
Published: (2018)
by: Zaharudin, Nurul Syahira
Published: (2018)
Optimization of synthesis parameters of mesoporous silica nanoparticles based on ionic liquid by experimental design and its application as drug delivery agent
by: Mohamed Isa, Eleen Dayana, et al.
Published: (2019)
by: Mohamed Isa, Eleen Dayana, et al.
Published: (2019)
Development of a drug delivery agent based on ionic liquids templated mesoporous silica nanoparticles
by: Mohamed Isa, Eleen Dayana
Published: (2017)
by: Mohamed Isa, Eleen Dayana
Published: (2017)
Mesoporous Silica Nanoparticles for Bioadsorption, Enzyme Immobilisation, and Delivery Carriers
by: Popat, A., et al.
Published: (2011)
by: Popat, A., et al.
Published: (2011)
A pH-responsive drug delivery system based on chitosan coated mesoporous silica nanoparticles
by: Popat, A., et al.
Published: (2012)
by: Popat, A., et al.
Published: (2012)
Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms
by: Chun, Xu, et al.
Published: (2018)
by: Chun, Xu, et al.
Published: (2018)
Mesoporous silica nanoparticle-templated ionic liquid as a drug carrier for ibuprofen and quercetin
by: Najihah Rameli,, et al.
Published: (2022)
by: Najihah Rameli,, et al.
Published: (2022)
Mesoporous silica nanoparticles as anticancer drug carriers in pancreatic cancer treatment
by: Chung, Shei Li
Published: (2025)
by: Chung, Shei Li
Published: (2025)
Discovery of ruthenium(ii) metallocompound and olaparib synergy for cancer combination therapy
by: Yusoh, Nur Aininie, et al.
Published: (2023)
by: Yusoh, Nur Aininie, et al.
Published: (2023)
Functionalized mesoporous silica nanoparticles templated by pyridinium ionic liquid for hydrophilic and hydrophobic drug release application
by: Zaharudin, Nurul Syahira, et al.
Published: (2020)
by: Zaharudin, Nurul Syahira, et al.
Published: (2020)
Ionic liquid templated mesoporous silica nanoparticles with tunable morphologies
by: Mohamed Isa, Eleen Dayana, et al.
Published: (2017)
by: Mohamed Isa, Eleen Dayana, et al.
Published: (2017)
Ordered mesoporous materials for drug delivery
by: Wang, Shaobin
Published: (2009)
by: Wang, Shaobin
Published: (2009)
Silica coated ionic liquid templated mesoporous silica nanoparticles
by: Isa, E. D. M., et al.
Published: (2017)
by: Isa, E. D. M., et al.
Published: (2017)
Electrospun poly (vinyl alcohol) nanofibers doped with mesoporous silica nanoparticles for controlled release of hydrophilic model drug
by: Md Fadilah, Nur Izzah, et al.
Published: (2019)
by: Md Fadilah, Nur Izzah, et al.
Published: (2019)
Adsorption and release of biocides with mesoporous silica nanoparticles
by: Popat, A., et al.
Published: (2012)
by: Popat, A., et al.
Published: (2012)
Synergy of ruthenium metallo-intercalator, [Ru(dppz)2(PIP)]2+, with PARP inhibitor Olaparib in non-small cell lung cancer cells
by: Yusoh, Nur Aininie, et al.
Published: (2023)
by: Yusoh, Nur Aininie, et al.
Published: (2023)
Effect of combination therapy of ruthenium polypyridyl complex, [Ru(dppz)2(PIP)]2+ and parp inhibitors against several cancer cell lines
by: Yusoh, Nur Aininie
Published: (2020)
by: Yusoh, Nur Aininie
Published: (2020)
Electrospinning of poly(vinyl) alcohol nanofibers containing mesoporous silica nanoparticles
by: Md Fadilah, Nur Izzah, et al.
Published: (2017)
by: Md Fadilah, Nur Izzah, et al.
Published: (2017)
Synthesis And Characterization Of Mesoporous Carbonated Hydroxyapatite For Drug Delivery Application
by: Mohammad, Nur Farahiyah
Published: (2017)
by: Mohammad, Nur Farahiyah
Published: (2017)
Efficient removal of lead from aqueous using hybrid graphite nanoflakes/mesoporous silica nanoparticles, amine functionalized mesoporous silica and graphite nanoflakes as adsorbents
by: Ahmad, Haslina, et al.
Published: (2020)
by: Ahmad, Haslina, et al.
Published: (2020)
Combining PARP inhibition with platinum, ruthenium or gold complexes for cancer therapy
by: Yusoh, Nur Aininie, et al.
Published: (2020)
by: Yusoh, Nur Aininie, et al.
Published: (2020)
Protein loaded mesoporous silica spheres as a controlled delivery platform
by: Ho, J., et al.
Published: (2008)
by: Ho, J., et al.
Published: (2008)
Advances in Multicompartment Mesoporous Silica Micro/Nanoparticles for Theranostic Applications.
by: Liu, J., et al.
Published: (2018)
by: Liu, J., et al.
Published: (2018)
Synthesis of nanorattles with layered double hydroxide core and mesoporous silica shell as delivery vehicles
by: Liu, Jian, et al.
Published: (2011)
by: Liu, Jian, et al.
Published: (2011)
Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides
by: Keane, Páraic M., et al.
Published: (2020)
by: Keane, Páraic M., et al.
Published: (2020)
Dependence of mesoporous silica properties on its template
by: Mohamed Isa, Eleen Dayana, et al.
Published: (2019)
by: Mohamed Isa, Eleen Dayana, et al.
Published: (2019)
Alginate coated mesoporous silica nanoparticles as oral delivery carrier of curcumin and quercetin to colon cancer: preparation, optimization, characterization, and anticancer activity
by: Alallam, Batoul, et al.
Published: (2025)
by: Alallam, Batoul, et al.
Published: (2025)
Nitrate uptake using mesoporous silica embedded with zero-valent palladium nanoparticles
by: Tong, C., et al.
Published: (2015)
by: Tong, C., et al.
Published: (2015)
Synthesis Of Silica Nanocolloids Drug Delivery System By Micelle Formation Approach
by: Wab, Hajarul Azwana Binti
Published: (2013)
by: Wab, Hajarul Azwana Binti
Published: (2013)
Applying the Taguchi Method to Optimise the Size of Silica Nanoparticles Entrapped with Rifampicin for a Drug Delivery System
by: Zainal, Nor Ain, et al.
Published: (2015)
by: Zainal, Nor Ain, et al.
Published: (2015)
Rough hollow mesoporous silica nanoparticles as carrier for agarwood oil to treat cancer cells
by: Khairudin, Nurul Hafizah, et al.
Published: (2018)
by: Khairudin, Nurul Hafizah, et al.
Published: (2018)
New modified mesoporous silica nanoparticles with bimetallic Ni-Zr for electroanalytical detection of dopamine
by: Mohamed Roduan, Mohamad Rafizie Aiman, et al.
Published: (2022)
by: Mohamed Roduan, Mohamad Rafizie Aiman, et al.
Published: (2022)
High-Yield Synthesis of Janus Dendritic Mesoporous Silica@Resorcinol-Formaldehyde Nanoparticles: A Competing Growth Mechanism
by: Qu, L., et al.
Published: (2017)
by: Qu, L., et al.
Published: (2017)
Stealth coating of nanoparticles in drug-delivery systems
by: Fam, See Yee, et al.
Published: (2020)
by: Fam, See Yee, et al.
Published: (2020)
Stealth coating of nanoparticles in drug delivery system
by: Fam, See Yee, et al.
Published: (2020)
by: Fam, See Yee, et al.
Published: (2020)
Similar Items
-
Synthesis, cytotoxicity and dna binding studies of ruthenium(ii) mixed-polypyridyl complexes
by: Harun, Siti Norain
Published: (2015) -
A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition
by: Gill, Martin R., et al.
Published: (2016) -
Nanosized mesoporous silicas for drug delivery
by: Li, Ka, et al.
Published: (2009) -
Ruthenium(II) Polypyridyl Complexes as FRET donors: structure- and sequence-selective DNA-binding and anticancer properties
by: Elgar, Christopher E., et al.
Published: (2023) -
Ruthenium(ii) Polypyridyl complexes as FRET donors: structure- and sequence-selective DNA binding and anti-cancer properties
by: E. Elgar, Christopher, et al.
Published: (2023)