Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation
We present a unique case of pneumococcal meningitis caused by serotype 15C, a non-vaccine serotype, which islong thought to be non-virulent. Our patient is a young lady with a known case of plaque psoriasis, presented with sudden onset of left oculomotor nerve palsy and severe headache two days prio...
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| Format: | Article |
| Language: | English |
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Universiti Putra Malaysia
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/95051/ http://psasir.upm.edu.my/id/eprint/95051/1/2021111910173864_MJMHS_0094.pdf |
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| author | Muhamad Damanhuri, Fatimahtuz Zahrah Aun, Evelyn Arushothy, Revathy Kandasamy, Thenmalar Zaini, Adillahtul Bushro Zakariah, Siti Zulaikha Masri, Siti Norbaya |
| author_facet | Muhamad Damanhuri, Fatimahtuz Zahrah Aun, Evelyn Arushothy, Revathy Kandasamy, Thenmalar Zaini, Adillahtul Bushro Zakariah, Siti Zulaikha Masri, Siti Norbaya |
| author_sort | Muhamad Damanhuri, Fatimahtuz Zahrah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | We present a unique case of pneumococcal meningitis caused by serotype 15C, a non-vaccine serotype, which islong thought to be non-virulent. Our patient is a young lady with a known case of plaque psoriasis, presented with sudden onset of left oculomotor nerve palsy and severe headache two days prior to admission. The clinical features were initially mimicking of brain tumour and brain aneurysm. The diagnosis of pneumococcal meningitis was confirmed by the bacterial antigen test and genome detection using multiplex PCR from the CSF. The blood culture also grew Streptococcus pneumoniae. Serotyping was performed on the isolate using Neufeld's Quellung method and it was identified as serotype 15C. Psoriatic skin disease was identified as a potential source of this invasive infection. |
| first_indexed | 2025-11-15T13:11:02Z |
| format | Article |
| id | upm-95051 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:11:02Z |
| publishDate | 2021 |
| publisher | Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-950512023-04-12T01:32:49Z http://psasir.upm.edu.my/id/eprint/95051/ Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation Muhamad Damanhuri, Fatimahtuz Zahrah Aun, Evelyn Arushothy, Revathy Kandasamy, Thenmalar Zaini, Adillahtul Bushro Zakariah, Siti Zulaikha Masri, Siti Norbaya We present a unique case of pneumococcal meningitis caused by serotype 15C, a non-vaccine serotype, which islong thought to be non-virulent. Our patient is a young lady with a known case of plaque psoriasis, presented with sudden onset of left oculomotor nerve palsy and severe headache two days prior to admission. The clinical features were initially mimicking of brain tumour and brain aneurysm. The diagnosis of pneumococcal meningitis was confirmed by the bacterial antigen test and genome detection using multiplex PCR from the CSF. The blood culture also grew Streptococcus pneumoniae. Serotyping was performed on the isolate using Neufeld's Quellung method and it was identified as serotype 15C. Psoriatic skin disease was identified as a potential source of this invasive infection. Universiti Putra Malaysia 2021 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/95051/1/2021111910173864_MJMHS_0094.pdf Muhamad Damanhuri, Fatimahtuz Zahrah and Aun, Evelyn and Arushothy, Revathy and Kandasamy, Thenmalar and Zaini, Adillahtul Bushro and Zakariah, Siti Zulaikha and Masri, Siti Norbaya (2021) Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation. Malaysian Journal of Medicine and Health Sciences, 17 (4). 442 - 444. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2021111910173864_MJMHS_0094.pdf |
| spellingShingle | Muhamad Damanhuri, Fatimahtuz Zahrah Aun, Evelyn Arushothy, Revathy Kandasamy, Thenmalar Zaini, Adillahtul Bushro Zakariah, Siti Zulaikha Masri, Siti Norbaya Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation |
| title | Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation |
| title_full | Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation |
| title_fullStr | Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation |
| title_full_unstemmed | Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation |
| title_short | Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation |
| title_sort | serotype 15c streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation |
| url | http://psasir.upm.edu.my/id/eprint/95051/ http://psasir.upm.edu.my/id/eprint/95051/ http://psasir.upm.edu.my/id/eprint/95051/1/2021111910173864_MJMHS_0094.pdf |