Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia
Congenital diaphragmatic hernia (CDH) is one of the most common major congenital anomalies. In utero visceral organ herniation into the thoracic cavity can result in lung hypoplasia and pulmonary hypertension may ensue. Post-natal mortality rates in isolated CDH remain high reaching up to 80% in sev...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Springer
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/94991/ http://psasir.upm.edu.my/id/eprint/94991/1/Role%20of%20predictive%20mortality%20calculator%20in%20antenatal%20assessment%20of%20congenital%20diaphragmatic%20hernia.pdf |
| _version_ | 1848862047048040448 |
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| author | Ishak, Azril Abu Hassan, Hasyma Mohd Jamil, Amilia Afzan Ramesh, Vairavan |
| author_facet | Ishak, Azril Abu Hassan, Hasyma Mohd Jamil, Amilia Afzan Ramesh, Vairavan |
| author_sort | Ishak, Azril |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Congenital diaphragmatic hernia (CDH) is one of the most common major congenital anomalies. In utero visceral organ herniation into the thoracic cavity can result in lung hypoplasia and pulmonary hypertension may ensue. Post-natal mortality rates in isolated CDH remain high reaching up to 80% in severe cases. Several prenatal predictors of morbidity and mortality have been proposed. Reliable predictive markers can aid clinicians in providing effective family counselling, prediction of survival, and propose therapeutic options. Decreased total fetal lung volume (TFLV) via magnetic resonance imaging (MRI) has been reported to be significantly associated with mortality. We report on 2 cases of CDH, with fetal MRI performed at third trimester, focusing on the TFLV and observed-to-expected TFLV. We would like to highlight the importance of predictive mortality calculator which provides statistical data for healthcare providers in counselling families and aids in risk-stratification. |
| first_indexed | 2025-11-15T13:10:48Z |
| format | Article |
| id | upm-94991 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:10:48Z |
| publishDate | 2021 |
| publisher | Springer |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-949912023-01-04T04:28:15Z http://psasir.upm.edu.my/id/eprint/94991/ Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia Ishak, Azril Abu Hassan, Hasyma Mohd Jamil, Amilia Afzan Ramesh, Vairavan Congenital diaphragmatic hernia (CDH) is one of the most common major congenital anomalies. In utero visceral organ herniation into the thoracic cavity can result in lung hypoplasia and pulmonary hypertension may ensue. Post-natal mortality rates in isolated CDH remain high reaching up to 80% in severe cases. Several prenatal predictors of morbidity and mortality have been proposed. Reliable predictive markers can aid clinicians in providing effective family counselling, prediction of survival, and propose therapeutic options. Decreased total fetal lung volume (TFLV) via magnetic resonance imaging (MRI) has been reported to be significantly associated with mortality. We report on 2 cases of CDH, with fetal MRI performed at third trimester, focusing on the TFLV and observed-to-expected TFLV. We would like to highlight the importance of predictive mortality calculator which provides statistical data for healthcare providers in counselling families and aids in risk-stratification. Springer 2021-09-28 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/94991/1/Role%20of%20predictive%20mortality%20calculator%20in%20antenatal%20assessment%20of%20congenital%20diaphragmatic%20hernia.pdf Ishak, Azril and Abu Hassan, Hasyma and Mohd Jamil, Amilia Afzan and Ramesh, Vairavan (2021) Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia. JOURNAL OF FETAL MEDICINE, 8 (3). pp. 211-215. ISSN 2348-1153; ESSN: 2348-8859 https://link.springer.com/article/10.1007/s40556-021-00315-5 10.1007/s40556-021-00315-5 |
| spellingShingle | Ishak, Azril Abu Hassan, Hasyma Mohd Jamil, Amilia Afzan Ramesh, Vairavan Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia |
| title | Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia |
| title_full | Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia |
| title_fullStr | Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia |
| title_full_unstemmed | Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia |
| title_short | Role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia |
| title_sort | role of predictive mortality calculator in antenatal assessment of congenital diaphragmatic hernia |
| url | http://psasir.upm.edu.my/id/eprint/94991/ http://psasir.upm.edu.my/id/eprint/94991/ http://psasir.upm.edu.my/id/eprint/94991/ http://psasir.upm.edu.my/id/eprint/94991/1/Role%20of%20predictive%20mortality%20calculator%20in%20antenatal%20assessment%20of%20congenital%20diaphragmatic%20hernia.pdf |