Pharmacologic downregulation of protein arginine methyltransferase1 expression by adenosine dialdehyde increases cell senescence in breast cancer

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Pharmacologic downregulation of protein arginine methyltransferase1 expression by adenosine dialdehyde increases cell senescence in breast cancer

We investigated the role of protein arginine methylation (PAM) in estrogen receptor (ER)-positive breast cancer cells through pharmacological intervention. Tamoxifen (TAM) or adenosine dialdehyde (ADOX), independently, triggered cell cycle arrest and down-regulated PAM, as reduced protein arginine m...

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Bibliographic Details
Main Authors:	Singh, Priya, Charles, Soniya, Madhavan, Thirumurthy, Munusamy-Ramanujam, Ganesh, Saraswathi, Nambiappan T., Arasu, Mariadhas Valan, Al-Dhabi, Naif Abdullah, Arshad, Aziz, Arockiaraj, Jesu, Mala, Kanchana
Format:	Article
Published:	Elsevier BV 2020
Online Access:	http://psasir.upm.edu.my/id/eprint/94569/

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