Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: Its activation coupled with G0/G1 phase cell cycle arrest.

QR Code

Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: Its activation coupled with G0/G1 phase cell cycle arrest.

Ethnopharmacological relevance: The plant Typhonium flagelliforme (TF), commonly known as ‘rodent tuber’ in Malaysia, is often used as traditional remedy for cancer, including leukemia. Aim of the study:Wehad previously identified morphologically that the linoleic acid rich fraction (DCM/F7) from...

Full description

Bibliographic Details
Main Authors:	Mohan, Syam, Abdul, Ahmad Bustaman, Abdelwahab, Siddig Ibrahim, Al-Zubairi, Adel Sharaf, Sukari, Mohamed Aspollah, Abdullah, Rasedee, Elhassan Taha, Manal Mohamed, Ibrahim, Mohamed Yousif, Syam, Suvitha
Format:	Article
Language:	English English
Published:	2010 Elsevier Ireland Ltd. All rights reserved 2010
Online Access:	http://psasir.upm.edu.my/id/eprint/9455/ http://psasir.upm.edu.my/id/eprint/9455/1/Typhonium%20flagelliforme%20induces%20apoptosis%20in%20CEMss%20cells%20via%20activation%20of%20caspase.pdf

Similar Items

Anti-Leukemic Effects of Typhonium Flagelliforme on Human Lymphoblastoid Cells (CEMss) and Murine Leukemic (WEHI-3) Model
by: Syam Mohan, Murali Mohan
Published: (2010)

Antibacterial and antioxidant activities of Typhonium flagelliforme (Lodd.) Blume tuber
by: Mohan, Syam, et al.
Published: (2008)

Investigations of antioxidant and antibacterial activities of Typhonium flagelliforme (Lodd.) Blume leaves.
by: Mohan, Syam, et al.
Published: (2008)

In vitro ultramorphological assessment of apoptosis on CEMss induce by linoleic acid-rich fraction form Typhonium flagelliforme tuber.
by: Mohan, Syam Murali, et al.
Published: (2010)

Anticancerous efect of Typhonium flagelliforme on human T4-lymphoblastoid cell line CEM-ss
by: Mohan, Syam, et al.
Published: (2008)

Extracts of Typhonium flagelliforme tubers for treatment of leukemia.
by: Abdul, Ahmad Bustamam, et al.
Published: (2010)

Typhonium flagelliforme inhibits the proliferation of murine leukemia WEHI-3 cells in vitro and induces apoptosis in vivo
by: Mohan, Syam, et al.
Published: (2010)

Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest
by: Ng, Kuan Beng, et al.
Published: (2013)

Analysis of preliminary phytochemical screening of Typhonium flagelliforme
by: Galehpardsari, Motahareh Nobakht, et al.
Published: (2010)

In Vitro Mass Propagation, Anti-Cancer Activity and Phytochemical Analysis of Typhonium Flagelliforme
by: Galehpardsari, Motahareh Nobakht
Published: (2009)

In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)
by: Lai , Choon Sheen
Published: (2010)

Nutritional Composition, Antioxidant Activity And Anticarcinogenic Effect Of Typhonium Flagelliforme (Nicholson 1029) Extract In Rat
by: Karuppiah, Thilakavathy
Published: (2000)

In vitro mass propagation of Typhonium flagelliforme as affected by plant growth regulators
by: Galehpardsari, Motahareh Nobakht, et al.
Published: (2009)

The growth of Typhonium flagelliforme treated with different levels of thidiazuron and N⁶ benzylaminopurine
by: Sunoto @ Hj. Faisal, Vajidah
Published: (2012)

Characterisation of Two Photosensitizing Compounds from Typhonium Flagelliforme Schott and Their Mode of Action in Inducing Cancer Cell Death
by: Ho, Anthony Siong Hock
Published: (2002)

Cytotoxic Effect of Girinimbine on HepG2 Cells
by: Mohan, Suvita Syam
Published: (2011)

Effects of organic and inorganic fertilizers on the growth and yield of rodent tuber (Typhonium flagelliforme)
by: Mat Napi, Mohamad Faiz
Published: (2015)

Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cellsthrough the intrinsic pathway with involvement of NF-kB signalling andG0/G1 cell cycle arrest : a bioassay-guided approach
by: Arbab, Ismail Adam, et al.
Published: (2013)

β-Mangostin induces p53-dependent G2/M cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway and NfkB suppression in MCF-7 cells
by: Syam, Suvitha, et al.
Published: (2014)

Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)

Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
by: Treude, Fabian, et al.
Published: (2014)

Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation.
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)

Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)

Regulation of p53-, Bcl-2- and Caspase-dependent Signaling Pathway in Xanthorrhizol-induced Apoptosis of HepG2 Hepatoma Cells
by: Tri Handayani,, et al.
Published: (2007)

Cardamonin induces apoptosis in human nasopharyngeal carcinoma cells via mitochondrial death pathway mediated by caspase-3 and caspase-8 activation, independent of caspase-9 signalling responses
by: Chiang, Michelle
Published: (2016)

Oncolysis of breast, liver and leukemia cancer cells using ethyl acetate and methanol extracts of goniothalamus umbrosus.
by: Abdelwahab, Siddig Ibrahim, et al.
Published: (2009)

Induction of Caspase-2 Activation by a DNA Enzyme Evokes Tumor Cell Apoptosis
by: Kim, Soo-Hyun, et al.
Published: (2012)

Zerumbone Exerts Antiproliferative Activity via Apoptosis on HepG2 Cells
by: Syed Alwi, Sharifah Sakinah, et al.
Published: (2007)

The growth suppressing effects of Girinimbine on Hepg2 involve induction of apoptosis and cell cycle arrest.
by: Syam, Suvitha, et al.
Published: (2011)

Biological activities of Pereskia bleo extracts
by: Abdelwahab, Siddig Ibrahim, et al.
Published: (2009)

Effects of nicotinamide and nilotinib on telomerase activity and telomere length associated with parp-1 regulation in k562 myeloid cell line
by: Muhammad, Nur Rasyidah
Published: (2023)

Apoptosis effect of girinimbine isolated from Murraya koenigii on lung cancer cells in vitro
by: Mohan, Syam, et al.
Published: (2013)

Inhibitor of caspase-activated DNase expression enhances caspase-activated DNase expression and inhibits oxidative stress-induced chromosome breaks at the mixed lineage leukaemia gene in nasopharyngeal carcinoma cells
by: Siaw, Shi Boon, et al.
Published: (2015)

In vitro anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin A, a chalcone isolated from Boesenbergia rotunda (L.) (fingerroot)
by: Mohd Isa, Noorain, et al.
Published: (2012)

Chemical Constituents of Garcinia Mangostana, G. Parvifolla, G. Griffitti and G. Diversifolia (Guttiferae) and Their Biological Activities
by: Tay, Bonnie Yen Ping
Published: (1996)

Expression of Temporin G, an antimicrobial peptide from Rana temporaria using an Intein self-cleavage system in Escherichia coli
by: Kagri, Sabah Mushrafin
Published: (2021)

Eupalitin from Asparagus falcatus (Linn.) has anticancer activity and induces activation of caspases 3/7 in human colorectal tumor cells
by: Ghalib, Gaza Murad, et al.
Published: (2013)

Cytotoxicty of zerumbone against liver cancer cell lines (HepG2) via apoptosis activity
by: Abdul Samad, Nozlena, et al.
Published: (2014)

Cell responses and hemocompatibility of g-HA/PLA composites
by: Li, J., et al.
Published: (2011)

Ethanol induces microglial cell death via the NOX/ROS/PARP/TRPM2 signalling pathway
by: Sha’fie, Muhammad Syahreel Azhad, et al.
Published: (2020)