Typhonium flagelliforme inhibits the proliferation of murine leukemia WEHI-3 cells in vitro and induces apoptosis in vivo

QR Code

Typhonium flagelliforme inhibits the proliferation of murine leukemia WEHI-3 cells in vitro and induces apoptosis in vivo

Typhonium flagelliforme (TF) is a tropical plant, traditionally used by the ethnic population of Malaysia for the cure of various cancers. This plant had shown to induce antiproliferative effect as well as apoptosis in cancer cells. However, there is no available information to address that TF aff...

Full description

Bibliographic Details
Main Authors:	Mohan, Syam, Abdul, Ahmad Bustamam, Abdel Wahab, Siddig Ibrahim, Al-Zubairi, Adel Sharaf, Sukari, Mohamed Aspollah, Abdullah, Rasedee, Elhassan Taha, Manal Mohamed, Ng, Kuan Beng, Mohd Isa, Nurbaity
Format:	Article
Language:	English English
Published:	2010 Elsevier Ltd. All rights reserved 2010
Online Access:	http://psasir.upm.edu.my/id/eprint/9453/ http://psasir.upm.edu.my/id/eprint/9453/1/Typhonium%20flagelliforme%20inhibits%20the%20proliferation%20of%20murine%20leukemia%20WEHI.pdf

Similar Items

Extracts of Typhonium flagelliforme tubers for treatment of leukemia.
by: Abdul, Ahmad Bustamam, et al.
Published: (2010)

Antibacterial and antioxidant activities of Typhonium flagelliforme (Lodd.) Blume tuber
by: Mohan, Syam, et al.
Published: (2008)

Investigations of antioxidant and antibacterial activities of Typhonium flagelliforme (Lodd.) Blume leaves.
by: Mohan, Syam, et al.
Published: (2008)

Anti-Leukemic Effects of Typhonium Flagelliforme on Human Lymphoblastoid Cells (CEMss) and Murine Leukemic (WEHI-3) Model
by: Syam Mohan, Murali Mohan
Published: (2010)

In vitro ultramorphological assessment of apoptosis on CEMss induce by linoleic acid-rich fraction form Typhonium flagelliforme tuber.
by: Mohan, Syam Murali, et al.
Published: (2010)

Anticancerous efect of Typhonium flagelliforme on human T4-lymphoblastoid cell line CEM-ss
by: Mohan, Syam, et al.
Published: (2008)

Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: Its activation coupled with G0/G1 phase cell cycle arrest.
by: Mohan, Syam, et al.
Published: (2010)

Analysis of preliminary phytochemical screening of Typhonium flagelliforme
by: Galehpardsari, Motahareh Nobakht, et al.
Published: (2010)

Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model
by: Rahman, Heshu Sulaiman, et al.
Published: (2015)

Oncolysis of breast, liver and leukemia cancer cells using ethyl acetate and methanol extracts of goniothalamus umbrosus.
by: Abdelwahab, Siddig Ibrahim, et al.
Published: (2009)

In vitro mass propagation of Typhonium flagelliforme as affected by plant growth regulators
by: Galehpardsari, Motahareh Nobakht, et al.
Published: (2009)

The growth of Typhonium flagelliforme treated with different levels of thidiazuron and N⁶ benzylaminopurine
by: Sunoto @ Hj. Faisal, Vajidah
Published: (2012)

Effects of Morinda citrifolia L. leaf extract on human T- lymphoblatic leukemia (JURKAT) cell and WEHI-3B cell- induced murine leukemia
by: Ahmadi, Negin
Published: (2016)

In Vitro Mass Propagation, Anti-Cancer Activity and Phytochemical Analysis of Typhonium Flagelliforme
by: Galehpardsari, Motahareh Nobakht
Published: (2009)

Effects of organic and inorganic fertilizers on the growth and yield of rodent tuber (Typhonium flagelliforme)
by: Mat Napi, Mohamad Faiz
Published: (2015)

In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)
by: Lai , Choon Sheen
Published: (2010)

Nutritional Composition, Antioxidant Activity And Anticarcinogenic Effect Of Typhonium Flagelliforme (Nicholson 1029) Extract In Rat
by: Karuppiah, Thilakavathy
Published: (2000)

Characterisation of Two Photosensitizing Compounds from Typhonium Flagelliforme Schott and Their Mode of Action in Inducing Cancer Cell Death
by: Ho, Anthony Siong Hock
Published: (2002)

In vitro ultramorphological assessment of apoptosis induced by Zerumbone on (HeLa)
by: Abdelwahab, Siddig Ibrahim, et al.
Published: (2009)

2020_Cytotoxic Effects and Apoptosis Induction of Betulinic Acid on WEHI-3B (Murine Myelomonocytic Leukemic) Cells

Anticancer and antimicrobial activities of zerumbone from the rhizomes of Zingiber zerumbut
by: Abdul, Ahmad Bustamam, et al.
Published: (2008)

In vivo and in vitro genotoxic effects of zerumbone.
by: Al-Zubairi, Adel Sharaf, et al.
Published: (2010)

Combination of zerumbone and cisplatin to treat cervical intraepithelial neoplasia in female BALB/c mice.
by: Abdul, Ahmad Bustamam, et al.
Published: (2009)

Biological activities of Pereskia bleo extracts
by: Abdelwahab, Siddig Ibrahim, et al.
Published: (2009)

Attenuation of cisplatin-induced hepatotoxicity in rats using zerumbone.
by: Ibrahim, Mohammed Yousif, et al.
Published: (2009)

Validated high performance liquid chromatographic (HPLC) method for analysis of zerumbone in plasma
by: Mohammad Eid, Eltayeb Elamin, et al.
Published: (2010)

In vivo anti-tumor effects of Azadirachta indica in rat liver cancer.
by: Mohamed Elhassan Taha , Manal, et al.
Published: (2009)

Anti-leukemic effects of zerumbone nanoparticle on human jurkat T lymphoblastoid cell lines in vitro and murine leukemic WEHI-3B model in vivo
by: Muhammad, Heshu Sulaiman Rahman
Published: (2014)

Serotonergic properties of the roots of Clerodendron capitatum
by: Abdelwahab, Siddig Ibrahim, et al.
Published: (2008)

Biological and phytochemical investigations of Goniothalamus umbrosus leaves hexane extract.
by: Abdelwahab, Siddig Ibrahim, et al.
Published: (2009)

Cytotoxic profiles of a nanodrug delivery based on 6-mercaptopurine-coated magnetite-peg nanoparticles towards leukemia (WEHI-3B) cell lines
by: Dorniani, Dena, et al.
Published: (2014)

Release behavior and toxicity profiles towards leukemia (WEHI-3B) cell lines 6-mercaptopurine-PEG-coated magnetite nanoparticles delivery systems
by: Dorniani, Dena, et al.
Published: (2014)

A composition for treating leukemia
by: Abdullah, Rasedee, et al.
Published: (2013)

Evaluation of the genotoxicity of zerumbone in cultured human peripheral blood lymphocytes
by: Al-Zubairi, Adel Sharaf, et al.
Published: (2010)

Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cellsthrough the intrinsic pathway with involvement of NF-kB signalling andG0/G1 cell cycle arrest : a bioassay-guided approach
by: Arbab, Ismail Adam, et al.
Published: (2013)

Zerumbone : A Natural Compound with Anti-Cholinesterase Activity.
by: Abdul, Ahmad Bustamam, et al.
Published: (2008)

The methalonic extract of Boesenbergia rotunda(L.) Mansf. and its major compound pinostrobin induces anti-ulcerogenic property in vivo: Possible involvement of indirect antioxidant action.
by: Md.Sukari, Mohd. Aspollah, et al.
Published: (2011)

The growth suppressing effects of Girinimbine on Hepg2 involve induction of apoptosis and cell cycle arrest.
by: Syam, Suvitha, et al.
Published: (2011)

Anti-leukemic activity of Newcastle disease virus strains AF2240 and V4-UPM in murine myelomonocytic leukemia in vivo

GC/MS determination of bioactive components and antibacterial properties of Goniothalamus umbrosus extracts
by: Abdelwahab, Siddig Ibrahim, et al.
Published: (2009)