Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination
Paediatric patients are considered vulnerable to radiation exposure and have a greater risk of developing radiation-induced cancers due to active growth cells. Radiation dose from a CT examination is the highest among other imaging modalities and can become harmful if unoptimised. Thus, the aim of t...
| Main Authors: | , , , , , , |
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| Format: | Article |
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Elsevier
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/94493/ |
| _version_ | 1848862012892774400 |
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| author | Abdul Karim, Muhammad Khalis Haspi Harun, Hanif Kayun, Zunaide Aljewaw, Osama Bagi Azizan, S. H.N. Rafiz, N. F.N.M. Muhammad, Nor Azura |
| author_facet | Abdul Karim, Muhammad Khalis Haspi Harun, Hanif Kayun, Zunaide Aljewaw, Osama Bagi Azizan, S. H.N. Rafiz, N. F.N.M. Muhammad, Nor Azura |
| author_sort | Abdul Karim, Muhammad Khalis |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Paediatric patients are considered vulnerable to radiation exposure and have a greater risk of developing radiation-induced cancers due to active growth cells. Radiation dose from a CT examination is the highest among other imaging modalities and can become harmful if unoptimised. Thus, the aim of this study is to evaluate the influence of paediatric size on SSDE value and to estimate cancer risk occurrence in specific organs of paediatric patients receiving CT chest examination. Data such as volume-weighted CT dose index (CTDIvol), dose length product (DLP) and patient's demography were retrospectively collected from a 64-slice CT scanner (Siemens Somatom Definition AS+) at University Malaya Medical Centre. A total of 120 patients were categorised into four age groups: G1 (0 – < 1 years), G2 (1 – < 5 years), G3 (5 – < 10 years), and G4 (10 – < 15 years). SSDE value was estimate in accordance with the American Association of Physicists, 2011 in Medicine (AAPM) report 204. The effective dose (E) and SSDENCICT obtained from National Cancer Institute Dosimetry System (NCICT) were then compared to the conventional SSDE value. The highest value of CTDIvol, DLP and E were found in group G4 with 4.9 ± 2.5, 185.0 ± 140.8, and 4.2 ± 2.0, respectively. Moreover, there is only slightly different of SSDE value between the G1 and G2 groups with a factor of 0.91. No significant difference (p > 0.05) was observed between the SSDEAAPM and SSDENCICT across all age groups. The cancer risk estimated shows thyroid organs receives the highest probability of cancer incidence in both the genders, which was calculated to be 2.1 for males and 3.9 for females per 100,000 procedures, respectively. Nevertheless, adequate justification of paediatric CT scans and dose optimisation are required to reduce unnecessary exposure and radiation-induced risks. |
| first_indexed | 2025-11-15T13:10:16Z |
| format | Article |
| id | upm-94493 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:10:16Z |
| publishDate | 2021 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-944932022-11-29T03:57:37Z http://psasir.upm.edu.my/id/eprint/94493/ Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination Abdul Karim, Muhammad Khalis Haspi Harun, Hanif Kayun, Zunaide Aljewaw, Osama Bagi Azizan, S. H.N. Rafiz, N. F.N.M. Muhammad, Nor Azura Paediatric patients are considered vulnerable to radiation exposure and have a greater risk of developing radiation-induced cancers due to active growth cells. Radiation dose from a CT examination is the highest among other imaging modalities and can become harmful if unoptimised. Thus, the aim of this study is to evaluate the influence of paediatric size on SSDE value and to estimate cancer risk occurrence in specific organs of paediatric patients receiving CT chest examination. Data such as volume-weighted CT dose index (CTDIvol), dose length product (DLP) and patient's demography were retrospectively collected from a 64-slice CT scanner (Siemens Somatom Definition AS+) at University Malaya Medical Centre. A total of 120 patients were categorised into four age groups: G1 (0 – < 1 years), G2 (1 – < 5 years), G3 (5 – < 10 years), and G4 (10 – < 15 years). SSDE value was estimate in accordance with the American Association of Physicists, 2011 in Medicine (AAPM) report 204. The effective dose (E) and SSDENCICT obtained from National Cancer Institute Dosimetry System (NCICT) were then compared to the conventional SSDE value. The highest value of CTDIvol, DLP and E were found in group G4 with 4.9 ± 2.5, 185.0 ± 140.8, and 4.2 ± 2.0, respectively. Moreover, there is only slightly different of SSDE value between the G1 and G2 groups with a factor of 0.91. No significant difference (p > 0.05) was observed between the SSDEAAPM and SSDENCICT across all age groups. The cancer risk estimated shows thyroid organs receives the highest probability of cancer incidence in both the genders, which was calculated to be 2.1 for males and 3.9 for females per 100,000 procedures, respectively. Nevertheless, adequate justification of paediatric CT scans and dose optimisation are required to reduce unnecessary exposure and radiation-induced risks. Elsevier 2021-11 Article PeerReviewed Abdul Karim, Muhammad Khalis and Haspi Harun, Hanif and Kayun, Zunaide and Aljewaw, Osama Bagi and Azizan, S. H.N. and Rafiz, N. F.N.M. and Muhammad, Nor Azura (2021) Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination. Radiation Physics and Chemistry, 188. art. no. 109685. pp. 1-8. ISSN 0969-806X; ESSN: 1879-0895 https://www.sciencedirect.com/science/article/pii/S0969806X21003352 10.1016/j.radphyschem.2021.109685 |
| spellingShingle | Abdul Karim, Muhammad Khalis Haspi Harun, Hanif Kayun, Zunaide Aljewaw, Osama Bagi Azizan, S. H.N. Rafiz, N. F.N.M. Muhammad, Nor Azura Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination |
| title | Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination |
| title_full | Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination |
| title_fullStr | Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination |
| title_full_unstemmed | Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination |
| title_short | Paediatric radiation dose and cancer risk associated with body effective diameter during CT thorax examination |
| title_sort | paediatric radiation dose and cancer risk associated with body effective diameter during ct thorax examination |
| url | http://psasir.upm.edu.my/id/eprint/94493/ http://psasir.upm.edu.my/id/eprint/94493/ http://psasir.upm.edu.my/id/eprint/94493/ |